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Protein Overview: UTP22

General Information:
Name(s) found: UTP22 / YGR090W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1237 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear outer membrane [IMPLink to PubMed article][IPILink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IC]
    ribosome biogenesis [IEA]
    rRNA processing [IEA][IMP]
    Molecular Function: snoRNA binding [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSVKRKAS ETSDQNIVKV QKKHSTQDST TDNGSKENDH SSQAINERTV PEQENDESDT  60
   61 SPESNEVATN TAATRHNGKV TATESYDIHI ARETAELFKS NIFKLQIDEL LEQVKLKQKH 120
  121 VLKVEKFLHK LYDILQEIPD WEEKSLAEVD SFFKNKIVSV PFVDPKPIPQ NTNYKFNYKK 180
  181 PDISLIGSFA LKAGIYQPNG SSIDTLLTMP KELFEKKDFL NFRCLHKRSV YLAYLTHHLL 240
  241 ILLKKDKLDS FLQLEYSYFD NDPLLPILRI SCSKPTGDSL SDYNFYKTRF SINLLIGFPY 300
  301 KVFEPKKLLP NRNCIRIAQE SKEQSLPATP LYNFSVLSSS THENYLKYLY KTKKQTESFV 360
  361 EATVLGRLWL QQRGFSSNMS HSGSLGGFGT FEFTILMAAL LNGGGINSNK ILLHGFSSYQ 420
  421 LFKGVIKYLA TMDLCHDGHL QFHSNPENSS SSPASKYIDE GFQTPTLFDK STKVNILTKM 480
  481 TVSSYQILKE YAGETLRMLN NVVQDQFSNI FLTNISRFDN LKYDLCYDVQ LPLGKYNNLE 540
  541 TSLAATFGSM ERVKFITLEN FLAHKITNVA RYALGDRIKY IQIEMVGQKS DFPITKRKVY 600
  601 SNTGGNHFNF DFVRVKLIVN PSECDKLVTK GPAHSETMST EAAVFKNFWG IKSSLRRFKD 660
  661 GSITHCCVWS TSSSEPIISS IVNFALQKHV SKKAQISNET IKKFHNFLPL PNLPSSAKTS 720
  721 VLNLSSFFNL KKSFDDLYKI IFQMKLPLSV KSILPVGSAF RYTSLCQPVP FAYSDPDFFQ 780
  781 DVILEFETSP KWPDEITSLE KAKTAFLLKI QEELSANSST YRSFFSRDES IPYNLEIVTL 840
  841 NILTPEGYGF KFRVLTERDE ILYLRAIANA RNELKPELEA TFLKFTAKYL ASVRHTRTLE 900
  901 NISHSYQFYS PVVRLFKRWL DTHLLLGHIT DELAELIAIK PFVDPAPYFI PGSLENGFLK 960
  961 VLKFISQWNW KDDPLILDLV KPEDDIRDTF ETSIGAGSEL DSKTMKKLSE RLTLAQYKGI1020
 1021 QMNFTNLRNS DPNGTHLQFF VASKNDPSGI LYSSGIPLPI ATRLTALAKV AVNLLQTHGL1080
 1081 NQQTINLLFT PGLKDYDFVV DLRTPIGLKS SCGILSATEF KNITNDQAPS NFPENLNDLS1140
 1141 EKMDPTYQLV KYLNLKYKNS LILSSRKYIG VNGGEKGDKN VITGLIKPLF KGAHKFRVNL1200
 1201 DCNVKPVDDE NVILNKEAIF HEIAAFGNDM VINFETD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BMS1 BRX1 CBF5 CHD1 CKA1 CKA2 CKB1 CKB2 DIP2 ECM16 EMG1 ENP1 ENP2 FUN12 HCA4 IFH1 IMD1 IMD3 IMD4 IMP3 IMP4 KEM1 KRE33 MAK21 MAK5 MPP10 MRD1 NAN1 NAT1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NSR1 PNO1 PRP43 PUF6 PWP1 PWP2 RPF2 RPL10 RPL15A RPL20B RPL27B RPL4B RPL5 RPP0 RPS11A, RPS11B RPS13 RPS1A RPS1B RPS22B RPS24A, RPS24B RPS3 RPS4B, RPS4A RPS6A, RPS6B RPS7A RPS8B, RPS8A RRP12 RRP5 RRP7 SOF1 STM1 TOP2 TSR1 UBP10 UTP10 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 YGR054W
    View Details Krogan NJ, et al. (2006) DHR2 IFH1 RRP7 TDA7 UBP10 UTP22 YGR251W
    View Details Gavin AC, et al. (2006) CMS1 DIP2 ENP1 ENP2 KRE33 KRR1 MRD1 NAN1 NOC4 NOP14 NOP58 PNO1 PWP2 ROK1 RRP9 UTP10 UTP13 UTP15 UTP18 UTP21 UTP22 UTP4 UTP6 UTP7 UTP8 UTP9
    View Details Gavin AC, et al. (2002) ADE4 ADH1 ARD1 ARX1 ASC1 BEM2 BFR2 BMS1 BRX1 BUD20 BUD21 CAB3 CBF5 CCM1 CFT2 CHD1 CIC1 CKA1 CKA2 CKB1 CKB2 CLU1 CMS1 CSL4 CYR1 CYS4 DBP10 DBP8 DBP9 DCP2 DIA4 DIM1 DIP2 DIS3 DRS1 EBP2 ECM16 ECM29 EHD3 EMG1 ENO1 ENP1 ENP2 ERB1 ERO1 ESF1 ESF2 FAP7 FIP1 FPR4 FYV4 GCN1 GEP3 GLC7 HAS1 HCA4 HDA1 HER1 HHF1, HHF2 HIS3 HOT1 HRR25 HSC82 HSL1 HTA2 IMP3 IMP4 INP2 IPI1 IPI3 ISW1 ISW2 KRE33 KRR1 LCP5 LHP1 LOC1 LRP1 LSG1 LTV1 MAK21 MAK5 MDN1 MIS1 MPP10 MRD1 MRP1 MRP10 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 MRT4 MTR3 MVD1 MYO1 NAM9 NAN1 NAP1 NAT1 NIP1 NIP7 NMD3 NOB1 NOC2 NOC3 NOC4 NOG1 NOG2 NOP1 NOP12 NOP14 NOP15 NOP16 NOP2 NOP4 NOP56 NOP58 NOP6 NOP7 NSA1 NSA2 NUG1 PAP1 PAP2 PET123 PFS2 PNO1 PRE6 PRE9 PRP43 PRT1 PSD2 PTA1 PTI1 PUF6 PUS1 PUS7 PWP2 RCL1 REF2 REI1 RET1 RIO2 RIX1 RIX7 RLP24 RLP7 RML2 RNA14 ROK1 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RRP4 RRP40 RRP42 RRP43 RRP45 RRP46 RRP6 RRP7 RRP9 RSA3 RSA4 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 RTG2 RTR1 RVB2 SAM1 SCL1 SDA1 SEC21 SEC7 SET2 SKI2 SKI3 SKI6 SKI7 SLX9 SNF2 SNF5 SNU13 SOF1 SPB1 SPB4 SPT16 SRO9 SRP1 SSA4 SSF1 SWI3 TIF1, TIF2 TIF35 TIF4631 TIF6 TSR1 TUB3 UBP10 URB1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 VPS1 YGL036W YGR054W YIR035C YOR059C YSH1 YTA7 YTM1
    View Details Ho Y, et al. (2002) AAC3 ADH2 AI1 AIM46 ARE1 ASF1 BCY1 BRX1 BUD3 CAR2 CCT2 CCT3 CCT6 CDC13 CDC16 CDC33 CIC1 CIN8 CKA1 CKA2 CKB1 CKB2 CLU1 CPR6 CYS4 DBP10 DIP2 EDE1 ELA1 ENP2 ERB1 ESL2 ESS1 FET4 FPR3 FUN12 GDE1 GID8 GND1 GRS1 GSP1 HAS1 HEF3 HHF1, HHF2 HHO1 HIR1 HOT1 HSP104 HTA2 HTB1 HXT6 IMD2 IMD3 IMD4 IPP1 KAP95 KRE33 KRI1 LCP5 LOC1 MAG1 MAG2 MDH1 MDN1 MES1 MGM101 MKT1 MMS4 MNP1 MPH1 MRPL1 MSC3 MSH2 MSS116 MUS81 NAN1 NHP2 NOC2 NOC3 NOP1 NOP12 NOP2 NOP4 NOP56 NOP7 NPL3 OYE2 PAA1 PDC6 PDI1 PNO1 POB3 POL2 POL5 PRP40 PTC2 PTC5 PUF6 PUP2 PWP1 PWP2 RAD53 RET1 RLI1 RPB3 RPC10 RPC82 RPF2 RPN1 RPO21 RRP12 RRP14 RRP5 RVB1 SEC23 SFP1 SMC3 SPT16 SPT2 SPT5 SRP1 SSD1 SSF1 STE23 SUP45 SWI4 TAF14 TBF1 TFG1 TFP1 TIF4631 TIF4632 TMA19 TOM1 TRL1 UBI4 UTP10 UTP11 UTP13 UTP14 UTP18 UTP21 UTP22 UTP30 UTP6 UTP7 VMR1 VPS73 WTM2 YHB1 YHR033W YRA1 YTA7
    View Details Qiu et al. (2008) BUD21 ENP1 IMP3 LCP5 RRP5 RRP9 SOF1 UTP10 UTP11 UTP13 UTP15 UTP21 UTP22 UTP4 UTP5 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UTP22 Huh WK, et al. (2003)
    View Data UTP22 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..164] deduced N/A No confident structure predictions are available.
    2 View Details [165..1237] Pfam 1000.0 Nrap protein No confident structure predictions are available.
    3 View Details [906..1033] MSA 1.050982 View MSA. No confident structure predictions are available.
    4 View Details [1034..1237] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.21555027517466 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.7166207083291 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.4031460115872 bayes_pls_golite062009
  • polynucleotide adenylyltransferase activity
    		•  0.986864608285919 bayes_pls_golite062009
  • binding
    		•  0.940725834840942 bayes_pls_golite062009
  • DNA binding
    		•  0.931982952649779 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.825883515331479 bayes_pls_golite062009
  • catalytic activity
    		•  0.718799603354138 bayes_pls_golite062009
  • transferase activity
    		•  0.245732860673913 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle