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View Structure Prediction Details

Protein: UTP22
Organism: Saccharomyces cerevisiae
Length: 1237 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP22.

Description E-value Query
Range
Subject
Range
NOL6_MOUSE - Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) - Mus musculus (Mouse)
0.0 [43..1235] [25..1133]
SPBC776.08c - Nrap
UTP22_SCHPO - U3 small nucleolar RNA-associated protein 22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
0.0 [33..1235] [2..1092]
gi|18539467, gi|... - gi|21218436|ref|NP_570611.1| nucleolar RNA-associated protein beta isoform [Homo sapiens], gi|185394...
0.0 [44..1086] [28..998]
UTP22 - Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis o...
UTP22_YEAST - U3 small nucleolar RNA-associated protein 22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
0.0 [1..1237] [1..1237]

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Predicted Domain #1
Region A:
Residues: [1-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSVKRKAS ETSDQNIVKV QKKHSTQDST TDNGSKENDH SSQAINERTV PEQENDESDT  60
   61 SPESNEVATN TAATRHNGKV TATESYDIHI ARETAELFKS NIFKLQIDEL LEQVKLKQKH 120
  121 VLKVEKFLHK LYDILQEIPD WEEKSLAEVD SFFKNKIVSV PFVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
RNA binding 3.21555027517466 bayes_pls_golite062009
nucleotidyltransferase activity 1.7166207083291 bayes_pls_golite062009
nucleic acid binding 1.4031460115872 bayes_pls_golite062009
polynucleotide adenylyltransferase activity 0.986864608285919 bayes_pls_golite062009
binding 0.940725834840942 bayes_pls_golite062009
DNA binding 0.931982952649779 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.825883515331479 bayes_pls_golite062009
catalytic activity 0.718799603354138 bayes_pls_golite062009
transferase activity 0.245732860673913 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [165-1237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKPIPQNTNY KFNYKKPDIS LIGSFALKAG IYQPNGSSID TLLTMPKELF EKKDFLNFRC  60
   61 LHKRSVYLAY LTHHLLILLK KDKLDSFLQL EYSYFDNDPL LPILRISCSK PTGDSLSDYN 120
  121 FYKTRFSINL LIGFPYKVFE PKKLLPNRNC IRIAQESKEQ SLPATPLYNF SVLSSSTHEN 180
  181 YLKYLYKTKK QTESFVEATV LGRLWLQQRG FSSNMSHSGS LGGFGTFEFT ILMAALLNGG 240
  241 GINSNKILLH GFSSYQLFKG VIKYLATMDL CHDGHLQFHS NPENSSSSPA SKYIDEGFQT 300
  301 PTLFDKSTKV NILTKMTVSS YQILKEYAGE TLRMLNNVVQ DQFSNIFLTN ISRFDNLKYD 360
  361 LCYDVQLPLG KYNNLETSLA ATFGSMERVK FITLENFLAH KITNVARYAL GDRIKYIQIE 420
  421 MVGQKSDFPI TKRKVYSNTG GNHFNFDFVR VKLIVNPSEC DKLVTKGPAH SETMSTEAAV 480
  481 FKNFWGIKSS LRRFKDGSIT HCCVWSTSSS EPIISSIVNF ALQKHVSKKA QISNETIKKF 540
  541 HNFLPLPNLP SSAKTSVLNL SSFFNLKKSF DDLYKIIFQM KLPLSVKSIL PVGSAFRYTS 600
  601 LCQPVPFAYS DPDFFQDVIL EFETSPKWPD EITSLEKAKT AFLLKIQEEL SANSSTYRSF 660
  661 FSRDESIPYN LEIVTLNILT PEGYGFKFRV LTERDEILYL RAIANARNEL KPELEATFLK 720
  721 FTAKYLASVR HTRTLENISH SYQFYSPVVR LFKRWLDTHL LLGHITDELA ELIAIKPFVD 780
  781 PAPYFIPGSL ENGFLKVLKF ISQWNWKDDP LILDLVKPED DIRDTFETSI GAGSELDSKT 840
  841 MKKLSERLTL AQYKGIQMNF TNLRNSDPNG THLQFFVASK NDPSGILYSS GIPLPIATRL 900
  901 TALAKVAVNL LQTHGLNQQT INLLFTPGLK DYDFVVDLRT PIGLKSSCGI LSATEFKNIT 960
  961 NDQAPSNFPE NLNDLSEKMD PTYQLVKYLN LKYKNSLILS SRKYIGVNGG EKGDKNVITG1020
 1021 LIKPLFKGAH KFRVNLDCNV KPVDDENVIL NKEAIFHEIA AFGNDMVINF ETD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 1000.0
Match: PF03813
Description: Nrap protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [906-1033]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQFYSPVVRL FKRWLDTHLL LGHITDELAE LIAIKPFVDP APYFIPGSLE NGFLKVLKFI  60
   61 SQWNWKDDPL ILDLVKPEDD IRDTFETSIG AGSELDSKTM KKLSERLTLA QYKGIQMNFT 120
  121 NLRNSDPN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1034-1237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTHLQFFVAS KNDPSGILYS SGIPLPIATR LTALAKVAVN LLQTHGLNQQ TINLLFTPGL  60
   61 KDYDFVVDLR TPIGLKSSCG ILSATEFKNI TNDQAPSNFP ENLNDLSEKM DPTYQLVKYL 120
  121 NLKYKNSLIL SSRKYIGVNG GEKGDKNVIT GLIKPLFKGA HKFRVNLDCN VKPVDDENVI 180
  181 LNKEAIFHEI AAFGNDMVIN FETD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle