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Protein Overview: MRPL1

General Information:
Name(s) found: MRPL1 / YDR116C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Mitochondrial ribosomal protein of the large subunit [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 285 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial large ribosomal subunit [IPILink to PubMed article][ISSLink to PubMed article]
    Biological Process: aerobic respiration [IEPLink to PubMed article][IMPLink to PubMed article]
    translation [ICLink to PubMed article]
    Molecular Function: structural constituent of ribosome [IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSVVAIPKI CVTGPARRCF FHTAKKLYAD DYKPAAMSSN APSLTKDQAK KRELKRLVQR  60
   61 KAEAKRPATA SPLYMPVTKA LRYLRAAEVG RPQSQQTINL TTLVVGERGT APLSGSVTFP 120
  121 KPLRYIKIAA FTNDESKLEE LREKYPNHLI GGADLVAKIK SGEISVDFDK AFATPDIVPA 180
  181 LQSQVARILG PRGVLPSVKK GTVSDDISSL LQESLGSMPF RQRGNSISIG VGKCYFTDRE 240
  241 ILQNIISARA AFKTAVDNQK SKKPNILSKT TLSSTHGPGI VIDFA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) IMG1 IMG2 MHR1 MRP20 MRP49 MRP7 MRPL1 MRPL13 MRPL15 MRPL16 MRPL17 MRPL20 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL6 MRPL7 MRPL8 MRPL9 RTC6 YML6
    View Details (MIPS) Mewes HW, et al. (2004) IMG1 IMG2 MNP1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL11 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL31 MRPL32 MRPL33 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL44 MRPL49 MRPL50 MRPL51 MRPL6 MRPL7 MRPL8 MRPL9 RML2 RTC6 YDR115W YML6
    View Details Krogan NJ, et al. (2006) IMG2 MRP20 MRPL1 MRPL10 MRPL15 MRPL25 MRPL3 MRPL4 MRPL40 MRPL9
    View Details Gavin AC, et al. (2002) ATG26 BEM2 BUD3 COP1 CYR1 HRR25 IMG1 IMG2 IML1 MHR1 MRH4 MRM1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL51 MRPL6 MRPL7 MRPL8 NIC96 NSP1 NUG1 NUP116 NUP159 NUP82 PRP43 RET2 ROM2 RTC6 SEC1 SEC26 SEC27 SIN4 SNF2 SWI3 SYP1 TAF5 UTP20 YDR115W YML6
    View Details Ho Y, et al. (2002) CIC1 CKA1 CKA2 CKB1 CKB2 DBP10 ENP2 GDE1 HHF1, HHF2 HOT1 KRI1 MRPL1 NOC3 NOP12 NOP2 NOP7 PDI1 POB3 POL2 PUF6 PWP1 RRP14 RRP5 SFP1 SPT16 SSF1 TIF4631 TRL1 UTP22 VMR1 VPS73 WTM2 YRA1
    View Details Qiu et al. (2008) COX14 IMG1 IMG2 MAM33 MHR1 MNP1 MRP1 MRP10 MRP13 MRP17 MRP2 MRP20 MRP21 MRP4 MRP49 MRP51 MRP7 MRPL1 MRPL10 MRPL11 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL31 MRPL32 MRPL33 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL44 MRPL49 MRPL50 MRPL51 MRPL6 MRPL7 MRPL8 MRPL9 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS8 MRPS9 NAM9 PET123 RML2 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 RTC6 SWS2 VAR1 YDR115W YML6 YMR31

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MRPL1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126]
    [211..285]    		 PSI-BLAST 207.70927 70S ribosome functional complex
    2 View Details [127..210] PSI-BLAST 207.70927 70S ribosome functional complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  9.98821526471491 bayes_pls_golite062009
  • structural molecule activity
    		•  9.4110731269774 bayes_pls_golite062009
  • binding
    		•  1.22345164833203 bayes_pls_golite062009
  • protein binding
    		•  0.542538198836039 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle