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Protein Overview: SWI3

General Information:
Name(s) found: SWI3 / YJL176C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 825 amino acids

    Gene Ontology:
    Cellular Component: SWI/SNF complex [TASLink to PubMed article]
    chromatin remodeling complex [TASLink to PubMed article]
    Biological Process: chromatin remodeling [TASLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTLGEGST VNASVDVDQH GNDNNSDSNA NAAVAGVANT DTAGEESQQQ DESLKDEATV  60
   61 PNTRDAESEA ITVTAKQQPT MQANKLDSQE TPSTEESRAQ NVFGQDNEDS DNLFGETESS 120
  121 VSNNEANTPS IPTNPVDNEN NKPAIKEDST IQDSNGDVKN MEDVKIQKEE EPENNTVIEG 180
  181 VKEESQPDEN TKEMDEVEED DEDDDQPMIS PDNSIFGDTK SESKQLGNTS SVANTPSEIP 240
  241 DAHKAEQEDI IEKTESVDKK VDSGEERNEQ EREIMNDHSK SANPKKTTIT RVEPETFEIP 300
  301 QAHEIVIPSY SKWFNLEKIH SIEVQSLPEF FTNRIPSKTP EVYMRYRNFM VNSYRLNPNE 360
  361 YFSVTTARRN VSGDAAALFR LHKFLTKWGL INYQVDSKLL PKNIEPPLTS QYSTRHDAPR 420
  421 GLFPFESYKP SVQLPDMAKL KKMMNTSDSE STLYKYLKES KRKYDEITHP PSTTDDENGD 480
  481 KNDNGGKMNN EVSTSTSMTG DANLLEEGET SRPLKKVKIL EQIDENWSKE DLQKLLKGIQ 540
  541 EFGADWYKVA KNVGNKSPEQ CILRFLQLPI EDKFLYGDGN GKGDNDNGLG PLKYAPHLPF 600
  601 SKSENPVLST IAFLVGLVNP KTVQSMTQRA IQSAESIKSQ KEEISDQKPI EHIKEGSEIA 660
  661 ISSLGYRSHI FATNEERQMN FLTNELIRLQ MEKLDAKLNH LKKLEKFMEL ERKTLERQQE 720
  721 NLLIQRLNFN QNSSKIVNVL SKCLNLISDS NINNSSVAEK EEIRSQIDHF KSMLSKPETL 780
  781 SIGKNPFNKP NIETGENHNG QSISNENDVK PISIEAPQFY RYWSA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP7 ARP9 RTT102 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82 TAF14
    View Details (MIPS) Mewes HW, et al. (2004) ARP7 ARP9 SNF11 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 TAF14
    View Details Krogan NJ, et al. (2006) SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82
    View Details Gavin AC, et al. (2006) ARP9 SNF11 SNF12 SNF5 SNF6 SWI1 SWI3
    View Details Gavin AC, et al. (2002) ADH1 ARP9 ATG26 BEM2 BUD3 CBF5 COP1 CYR1 DIM1 ECM16 EMG1 ENP1 FKS1 GCD6 HRR25 IMG1 IMG2 IML1 IMP3 IMP4 KRE33 KRR1 LTV1 MHR1 MPP10 MRH4 MRM1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL13 MRPL16 MRPL17 MRPL19 MRPL20 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL51 MRPL6 MRPL7 MRPL8 NAT1 NEM1 NOB1 NOC4 NOP1 NOP14 NUG1 PNO1 PRP43 RCL1 RET2 RIO2 ROM2 RRP12 RTC6 SAM1 SEC1 SEC26 SEC27 SIN4 SLX9 SNF12 SNF2 SNF5 SNF6 SOF1 SWI1 SWI3 SWP82 SYP1 TAF5 TSR1 UTP15 UTP20 UTP22 UTP6 UTP7 VPS1 YDR115W YGR054W YML6
    View Details Qiu et al. (2008) ARP7 ARP9 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 TAF14

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SWI3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..6]
    [229..308]    		 ORFEUS 14.29 No description for 1l8mA was found.
    2 View Details [7..79] ORFEUS 14.29 No description for 1l8mA was found.
    3 View Details [80..158] ORFEUS 14.29 No description for 1l8mA was found.
    4 View Details [159..228] ORFEUS 14.29 No description for 1l8mA was found.
    5 View Details [309..409] deduced N/A No confident structure predictions are available.
    6 View Details [410..485] PSI-BLAST 5.154902 No description for 1h8qA_ was found.
    7 View Details [486..596] ORFEUS 9.36 c-Myb, DNA-binding domain
    8 View Details [597..825] MSA 1.040987 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle