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Protein Overview: TSR1

General Information:
Name(s) found: TSR1 / YDL060W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 788 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    Biological Process: ribosome biogenesis [IMPLink to PubMed article][RCALink to PubMed article]
    rRNA processing [IMPLink to PubMed article]
    Molecular Function: ribonucleoprotein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGHSHRSSL KNGHKSYKSK HASKGALKRL YKGKVEKEPV GTGKPDKQVS KLQRKNKAKQ  60
   61 LRAQRILDSI ENRKLFEGKN GAAKIITIVP LVNDLDPLDI LYKLLKCADD EGIMVQEVDS 120
  121 KRIFNVHIKK FKSNLKIIIP DMTNFLNILD CAKVADFVVF GLSGVQEVDE EFGEQIIRAL 180
  181 ELQGIASYIG VISNLSAVHE KEKFQLDVKQ SLESYFKHFF PSEERVYNLE KNSDALNVLR 240
  241 TLCQRLPRSI NWRDNRGYVV ADFVDFVETS PDSGDLVIEG TVRGIGFNAN RLVHIPDFGD 300
  301 FQLNKIEKIS ESSQKRKIIK EKATDSLSLE LDLQTVFESN MNRDTLDEYA PEGTEDWSDY 360
  361 DEDFEYDGLT TARYDDHGFL PGREQTSKKA AVPKGTSDYQ AKWYLDDVID ANEEEEAEQT 420
  421 NGKDETMMEI DDEMMVEQDN EEVAGDEEYD IEDNEGFEEL SPEEEERQLR EFRDMEKEDR 480
  481 EFPDEIELEP SESAIERLKR YRGLKNLYNC DWQVDEKDPS SPAEWKRLLR IGNYKNTKNR 540
  541 IIKETKNEAQ AIAGDRIRMF IRFPKFLLEK IQDPKQLLFA VYGLLLHEHK NAVVNFSLQR 600
  601 WEQYDKPVPS QEPIVVQYGV RRYTIQPLFS QGSNSPNNVH KYERFLHPDT VSVATCIAPV 660
  661 DFTQSPAIFF KPSPTDAKNI ELIGHGTFLN ADHSRILAKR AILTGHPFRF HKTVVTVRYM 720
  721 FFRPEDVEWF KSIPLFTKSG RSGFIKESLG THGYFKATFD GKLSAQDVVA MSLYKRMWPM 780
  781 PSLPWNGM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) DIM1 ECM16 ENP1 HRR25 KRE33 KRI1 KRR1 LTV1 NOB1 NPL3 PNO1 PRP43 RIO2 RPS11A, RPS11B RPS13 RPS17B RPS1A RPS24A, RPS24B RPS4B, RPS4A RPS8B, RPS8A RPS9B RRP12 SLX9 TSR1 UTP22 YGR054W
    View Details Krogan NJ, et al. (2006) APN2 BFR1 BRX1 BUR2 LOC1 NHP6A PRK1 RIM1 SGV1 SPB1 TMA64 TSR1
    View Details Gavin AC, et al. (2006) HRR25 LTV1 NOB1 RIO2 TSR1
    View Details Gavin AC, et al. (2002) ADE4 ADH1 AEP1 AEP2 ARP9 ASC1 ATP22 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 GCN1 HCA4 HHF1, HHF2 HRP1 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP14 NOP56 NOP58 NOP6 PAA1 PFK1 PNO1 PRE6 PRE9 PRP43 PTC3 PWP2 RAD50 RCL1 RIO2 RML2 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SES1 SLX9 SNF12 SNF2 SNF5 SNF6 SOF1 SWI1 SWI3 SWP82 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 VPS1 VPS15 YGR054W YOR059C
    View Details Ho Y, et al. (2002) ABP1 ACO1 AIM41 ATP4 BUD14 CAR2 CBF5 CBP2 CCM1 CDC25 CDC33 CIC1 CKA2 COR1 CRZ1 CYS4 DBP7 DCP1 DCP2 DNM1 DRS1 EDC3 EDE1 EGD2 ENP1 ENP2 ERB1 FPR3 GAS1 GBP2 GCN3 GLC7 GPH1 HAS1 HHF1, HHF2 HMO1 HRR25 HSP104 HTB1 HTB2 HXT7 HYP2 IMD1 IMD3 IPP1 IRA1 ISA1 KAP95 KRE33 KRI1 KRR1 LOC1 LSP1 LTV1 MDH1 MDS3 MGE1 MGM101 MNP1 MSS116 NOB1 NOC2 NOP12 NOP2 NOP58 NOP6 NOP7 NPL3 NSA1 NUG1 OYE2 PET127 PEX19 PIL1 PIN4 POL5 PRP43 PTC4 PUF3 PUF6 PWP1 RAS2 RIO2 RLI1 RPC19 RPF2 RPM2 RRP12 RRP5 SAP185 SAP190 SAS10 SEC2 SEC23 SES1 SFB3 SGM1 SIT4 TGL1 TIF1, TIF2 TIF4631 TIF6 TMA19 TRA1 TSR1 URB1 URB2 UTP10 UTP20 VMA4 YBR225W YER138C YPP1 YRA1 YTM1
    View Details Qiu et al. (2008) BUD20 HMS2 RIA1 RKI1 RPL10 RPL11B RPL12B, RPL12A RPL13A RPL13B RPL14A RPL14B RPL15A RPL16A RPL16B RPL17A RPL17B RPL19B, RPL19A RPL1A, RPL1B RPL20A RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL25 RPL26A RPL26B RPL27B RPL28 RPL29 RPL2A, RPL2B RPL30 RPL31A RPL31B RPL32 RPL33A RPL33B RPL34A RPL35A, RPL35B RPL36A RPL36B RPL37A RPL37B RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL5 RPL6A RPL6B RPL8A RPL8B RPL9A RPL9B RPP0 RPP1B RPP2A RPS0A RPS0B RPS10B RPS11A, RPS11B RPS12 RPS13 RPS14B RPS15 RPS16B, RPS16A RPS17A RPS17B RPS18B, RPS18A RPS19A RPS19B RPS1A RPS1B RPS2 RPS21B RPS22A RPS23B, RPS23A RPS24A, RPS24B RPS25A RPS25B RPS26A RPS26B RPS27A RPS27B RPS29A RPS30B, RPS30A RPS31 RPS4B, RPS4A RPS6A, RPS6B RPS7A RPS7B RPS8B, RPS8A RRP5 TSR1 UTP6 YPL199C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TSR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] deduced N/A No confident structure predictions are available.
    2 View Details [80..310] ab initio 9.6 No description for 1d2eA was found.
    3 View Details [311..511] MSA 21.068997 View MSA. No confident structure predictions are available.
    4 View Details [512..788] MSA 3.055938 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle