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Protein Overview: ARP9

General Information:
Name(s) found: ARP9 / YMR033W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 467 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    SWI/SNF complex [IPILink to PubMed article]
    RSC complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: ATP-dependent chromatin remodeling [IDALink to PubMed article]
    Molecular Function: DNA-dependent ATPase activity [IDALink to PubMed article]
    general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPFRQDSIL IIYPRSQTTL VQFGLNEETF TVPELEIPTQ IYRTTRQDGS YTYHSTNKDN  60
   61 KAELIKPIQN GEIIDISAFT QFLRLIFVSI LSDRANKNQD AFEAELSNIP LLLITHHSWS 120
  121 QSDLEIITQY VFESLEINNL IQLPASLAAT YSMISLQNCC IIDVGTHHTD IIPIVDYAQL 180
  181 DHLVSSIPMG GQSINDSLKK LLPQWDDDQI ESLKKSPIFE VLSDDAKKLS SFDFGNENED 240
  241 EDEGTLNVAE IITSGRDTRE VLEERERGQK VKNVKNSDLE FNTFWDEKGN EIKVGKQRFQ 300
  301 GCNNLIKNIS NRVGLTLDNI DDINKAKAVW ENIIIVGGTT SISGFKEALL GQLLKDHLII 360
  361 EPEEEKSKRE EEAKSVLPAA TKKKSKFMTN STAFVPTIEY VQCPTVIKLA KYPDYFPEWK 420
  421 KSGYSEIIFL GAQIVSKQIF THPKDTFYIT REKYNMKGPA ALWDVQF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP7 ARP9 HTL1 NFI1 NPL6 RSC1 RSC2 RSC3 RSC30 RSC4 RSC58 RSC6 RSC8 RSC9 RTT102 SFH1 SNF12 SNF2 SNF5 SNF6 STH1 SWI1 SWI3 SWP82 VPS1
    View Details (MIPS) Mewes HW, et al. (2004) ARP7 ARP9 RSC1 RSC2 RSC4 RSC6 RSC8 SAS5 SFH1 SNF11 SNF12 SNF2 SNF5 SNF6 STH1 SWI1 SWI3 TAF14
    View Details Krogan NJ, et al. (2006) ARP7 ARP9 ATG16 CSH1 GRS2 HTL1 MGR1 NFI1 NPL6 PCL9 RIM15 RSC1 RSC2 RSC3 RSC4 RSC58 RSC6 RSC8 RSC9 RTT102 SFH1 STH1 URC2 YIL177C
    View Details Gavin AC, et al. (2006) ARP9 SNF11 SNF12 SNF5 SNF6 SWI1 SWI3
    View Details Gavin AC, et al. (2002) ARP9 BEM2 DIM1 ENP1 HRR25 LTV1 NOB1 PNO1 RIO2 RRP12 SNF12 SNF2 SNF5 SNF6 SWI1 SWI3 SWP82 TSR1 VPS1 YGR054W
    View Details Qiu et al. (2008) ARP7 ARP9 RSC1 RSC2 RSC4 RSC6 RSC8 RTT102 SFH1 SNF11 SNF12 SNF2 SNF5 SNF6 STH1 SWI1 SWI3 SWP82 TAF14

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIH1 control 2 McCusker D, et al (2007)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145]
    [371..467]    		 PSI-BLAST 1040.9691 Actin
    2 View Details [146..370] PSI-BLAST 1040.9691 Actin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural molecule activity
    		•  2.37892721989886 bayes_pls_golite062009
  • binding
    		•  2.11855816699924 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09111975841662 bayes_pls_golite062009
  • protein binding
    		•  2.00711904074672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.84294882554466 bayes_pls_golite062009
  • DNA binding
    		•  1.70014394990425 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  1.59975673209166 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  1.59975673209166 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.55370373529628 bayes_pls_golite062009
  • transcription activator activity
    		•  1.35676801272576 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.20454823547711 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.19428728049016 bayes_pls_golite062009
  • kinase activity
    		•  1.11102445353265 bayes_pls_golite062009
  • transcription factor activity
    		•  1.06678984888387 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.00147083605664 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.795304313835604 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.574998559133169 bayes_pls_golite062009
  • nucleosome binding
    		•  0.329990231856661 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • actin binding
    		•  0.167605789198131 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.123282448317819 bayes_pls_golite062009
  • transferase activity
    		•  0.105619024604158 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.0571907728331915 bayes_pls_golite062009
  • chromatin binding
    		•  0.0489277194984092 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.0304569608189402 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle