YRC Public Data Repository - Protein Structure Prediction

Protein:	ARP9
Organism:	Saccharomyces cerevisiae
Length:	467 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARP9.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..403]	[1..375]
ACT3_BOMMO - Actin, cytoplasmic A3 OS=Bombyx mori PE=3 SV=3	0.0	[1..403]	[1..375]
gi\|19526211, gi\|... - gi\|19526213\|gb\|AAL89658.1\|AF286060_1 cytoplasmic actin A3a1 [Helicoverpa zea], gi\|19526211\|gb\|AAL896... gi\|28070937 - gi\|28070937\|emb\|CAD58315.1\| non-muscle actin [Manduca sexta] ACT3A_HELAM - Actin, cytoplasmic A3a OS=Helicoverpa armigera GN=actA3a PE=2 SV=1 gi\|154091302 - gi\|154091302\|gb\|ABS57458.1\| actin 1 [Heliconius erato]	0.0	[1..403]	[1..375]
gi\|194130965, gi... - gi\|195340496\|ref\|XP_002036849.1\| GM12447 [Drosophila sechellia], gi\|194130965\|gb\|EDW53008.1\| GM12447... gi\|195401955, gi... - gi\|195401955\|ref\|XP_002059576.1\| GJ14747 [Drosophila virilis], gi\|194147283\|gb\|EDW62998.1\| GJ14747 [... gi\|195432731, gi... - gi\|195432731\|ref\|XP_002064370.1\| GK20124 [Drosophila willistoni], gi\|194160455\|gb\|EDW75356.1\| GK2012... gi\|195480603, gi... - gi\|195480603\|ref\|XP_002101323.1\| Act57B [Drosophila yakuba], gi\|194188847\|gb\|EDX02431.1\| Act57B [Dro... gi\|89473786, gi\|... - gi\|89473786\|gb\|ABD72705.1\| putative actin [Acyrthosiphon pisum], gi\|187109134\|ref\|NP_001119672.1\| ac... gi\|195565315, gi... - gi\|195565315\|ref\|XP_002106247.1\| GD16764 [Drosophila simulans], gi\|194203621\|gb\|EDX17197.1\| GD16764 ... ACT4_BOMMO - Actin, cytoplasmic A4 OS=Bombyx mori GN=A4 PE=2 SV=1 gi\|91088365, gi\|... - gi\|91088369\|ref\|XP_976070.1\| PREDICTED: similar to Actin-5C isoform 3 [Tribolium castaneum], gi\|9108... gi\|220947776, gi... - gi\|220957086\|gb\|ACL91086.1\| Act5C-PA [synthetic construct], gi\|220947776\|gb\|ACL86431.1\| Act5C-PA [sy... gi\|170048737, gi... - gi\|170048737\|ref\|XP_001870756.1\| conserved hypothetical protein [Culex quinquefasciatus], gi\|1678707... gi\|190648678, gi... - gi\|194889160\|ref\|XP_001977029.1\| GG18797 [Drosophila erecta], gi\|190648678\|gb\|EDV45956.1\| GG18797 [D... gi\|193892986, gi... - gi\|195046398\|ref\|XP_001992145.1\| GH24372 [Drosophila grimshawi], gi\|193892986\|gb\|EDV91852.1\| GH24372... gi\|125981707\|ref... - GA17886-PA [Drosophila pseudoobscura], GA17886 [Drosophila pseudoobscura pseudoobscura] gi\|193907820, gi... - gi\|195129856\|ref\|XP_002009370.1\| GI15312 [Drosophila mojavensis], gi\|193907820\|gb\|EDW06687.1\| GI1531... gi\|195166956, gi... - gi\|195166956\|ref\|XP_002024300.1\| GL14888 [Drosophila persimilis], gi\|194107673\|gb\|EDW29716.1\| GL1488... FBpp0311818, Act... - The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042). It is a ... ACT5C_ANOGA - Actin-5C OS=Anopheles gambiae GN=Act5C PE=2 SV=1 gi\|54643168, gi\|... - gi\|54643168\|gb\|EAL31912.1\| GA17886 [Drosophila pseudoobscura pseudoobscura], gi\|125981707\|ref\|XP_001... gi\|157128681, gi... - gi\|157128681\|ref\|XP_001655176.1\| actin [Aedes aegypti], gi\|157128679\|ref\|XP_001655175.1\| actin [Aede... gi\|52630919 - gi\|52630919\|gb\|AAU84923.1\| putative actin [Toxoptera citricida] ACT3B_HELAM - Actin-A3b, cytoplasmic OS=Helicoverpa armigera GN=actA3b PE=2 SV=1 gi\|118780938, gi... - gi\|58381342\|ref\|XP_311177.2\| ENSANGP00000019055 [Anopheles gambiae str. PEST], gi\|55242984\|gb\|EAA068...	0.0	[1..403]	[1..375]
ACT5_XENLA - Actin, cytoplasmic type 5 OS=Xenopus laevis PE=3 SV=1	0.0	[1..403]	[1..375]
gi\|80751139, gi\|... - gi\|80751139\|ref\|NP_001032193.1\| hypothetical protein LOC641320 [Danio rerio], gi\|78070743\|gb\|AAI0784... ACT4_ARTSX - Actin, clone 403 OS=Artemia sp. PE=2 SV=1	0.0	[1..403]	[1..375]
ACT_COLSC - Actin OS=Coleochaete scutata PE=2 SV=1	0.0	[1..403]	[1..376]
gi\|3421457 - gi\|3421457\|gb\|AAC32224.1\| cytoplasmic actin [Dreissena polymorpha]	0.0	[1..403]	[1..375]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[3..403]	[1..374]

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Predicted Domain #1

Region A:
Residues: [1-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPFRQDSIL IIYPRSQTTL VQFGLNEETF TVPELEIPTQ IYRTTRQDGS YTYHSTNKDN  60
   61 KAELIKPIQN GEIIDISAFT QFLRLIFVSI LSDRANKNQD AFEAELSNIP LLLITHHSWS 120
  121 QSDLEIITQY VFESLEINNL IQLPA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [371-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEAKSVLPAA TKKKSKFMTN STAFVPTIEY VQCPTVIKLA KYPDYFPEWK KSGYSEIIFL  60
   61 GAQIVSKQIF THPKDTFYIT REKYNMKGPA ALWDVQF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1040.9691
Match:	1yagA_
Description:	Actin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural molecule activity	2.37892721989886	bayes_pls_golite062009
binding	2.11855816699924	bayes_pls_golite062009
transcription regulator activity	2.09111975841662	bayes_pls_golite062009
protein binding	2.00711904074672	bayes_pls_golite062009
nucleic acid binding	1.84294882554466	bayes_pls_golite062009
DNA binding	1.70014394990425	bayes_pls_golite062009
histone acetyltransferase activity	1.59975673209166	bayes_pls_golite062009
lysine N-acetyltransferase activity	1.59975673209166	bayes_pls_golite062009
structural constituent of cytoskeleton	1.55370373529628	bayes_pls_golite062009
transcription activator activity	1.35676801272576	bayes_pls_golite062009
cytoskeletal protein binding	1.20454823547711	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.19428728049016	bayes_pls_golite062009
kinase activity	1.11102445353265	bayes_pls_golite062009
transcription factor activity	1.06678984888387	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.00147083605664	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.795304313835604	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.574998559133169	bayes_pls_golite062009
nucleosome binding	0.329990231856661	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
actin binding	0.167605789198131	bayes_pls_golite062009
carbohydrate kinase activity	0.123282448317819	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009
N-acetyltransferase activity	0.0571907728331915	bayes_pls_golite062009
chromatin binding	0.0489277194984092	bayes_pls_golite062009
unfolded protein binding	0.0304569608189402	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [146-370]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLAATYSMIS LQNCCIIDVG THHTDIIPIV DYAQLDHLVS SIPMGGQSIN DSLKKLLPQW  60
   61 DDDQIESLKK SPIFEVLSDD AKKLSSFDFG NENEDEDEGT LNVAEIITSG RDTREVLEER 120
  121 ERGQKVKNVK NSDLEFNTFW DEKGNEIKVG KQRFQGCNNL IKNISNRVGL TLDNIDDINK 180
  181 AKAVWENIII VGGTTSISGF KEALLGQLLK DHLIIEPEEE KSKRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1040.9691
Match:	1yagA_
Description:	Actin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: