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The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. Any transcription regulator activity that prevents or downregulates transcription. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. Functions to initiate or regulate RNA polymerase I transcription. The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed. Functions to initiate or regulate RNA polymerase II transcription. Any activity that brings about termination of transcription. Any transcription regulator activity required for initiation or upregulation of transcription. Functions to initiate or regulate RNA polymerase III transcription. Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell. null Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity. null

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transcription regulator activity
Acc: GO:0030528
Aspect: Molecular Function
Desc: Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.
Synonyms:
  • transcriptional regulator activity
Proteins in PDR annotated with:
   This term: 1242 [Search]
   Term or descendants: 9716 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030528 - transcription regulator activity (interactive image map)
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