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Protein Overview: ENP1

General Information:
Name(s) found: ENP1 / YBR247C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 483 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear outer membrane [IMPLink to PubMed article]
    nucleolus [TASLink to PubMed article]
    preribosome, small subunit precursor [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    rRNA processing [IPILink to PubMed article]
    Molecular Function: snoRNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARASSTKAR KQRHDPLLKD LDAAQGTLKK INKKKLAQND AANHDAANEE DGYIDSKASR  60
   61 KILQLAKEQQ DEIEGEELAE SERNKQFEAR FTTMSYDDED EDEDEDEEAF GEDISDFEPE 120
  121 GDYKEEEEIV EIDEEDAAMF EQYFKKSDDF NSLSGSYNLA DKIMASIREK ESQVEDMQDD 180
  181 EPLANEQNTS RGNISSGLKS GEGVALPEKV IKAYTTVGSI LKTWTHGKLP KLFKVIPSLR 240
  241 NWQDVIYVTN PEEWSPHVVY EATKLFVSNL TAKESQKFIN LILLERFRDN IETSEDHSLN 300
  301 YHIYRAVKKS LYKPSAFFKG FLFPLVETGC NVREATIAGS VLAKVSVPAL HSSAALSYLL 360
  361 RLPFSPPTTV FIKILLDKKY ALPYQTVDDC VYYFMRFRIL DDGSNGEDAT RVLPVIWHKA 420
  421 FLTFAQRYKN DITQDQRDFL LETVRQRGHK DIGPEIRREL LAGASREFVD PQEANDDLMI 480
  481 DVN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ASC1 BFR2 BMS1 DIM1 ECM16 EMG1 ENP1 ENP2 HRP1 HRR25 IMP3 KAP104 KRE33 KRR1 LTV1 MPP10 NAB2 NAN1 NOB1 NOC4 NOP1 NOP14 PNO1 RIO2 RPS13 RPS24A, RPS24B RPS3 RPS7A RRP12 SOF1 TSR1 UTP10 UTP15 UTP20 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 YNL035C
    View Details Krogan NJ, et al. (2006) ENP1 LTV1 LYS9 YAR1
    View Details Gavin AC, et al. (2006) DIP2 ENP1 ENP2 KRE33 KRR1 NOC4 NOP14 ROK1 UTP22 UTP6 UTP7
    View Details Gavin AC, et al. (2002) ADE4 ADH1 ARP9 ASC1 BEM2 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HRR25 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAA1 PAP1 PFK1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTC3 PTI1 PWP2 RAD50 RCL1 REF2 RIO2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SNF12 SNF2 SNF5 SNF6 SOF1 SRO9 SWI1 SWI3 SWP82 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 VPS1 VPS15 YGR054W YOR059C YSH1
    View Details Ho Y, et al. (2002) AAT2 ABP1 ACO1 ACS2 ADH4 ADR1 AFG3 AIM41 ALA1 ARC1 ARG4 ATP4 AYR1 BGL2 BMS1 BUD14 CAR2 CBP6 CDC25 CDC53 CDC60 CIC1 CKA2 COF1 COR1 CPR1 CRZ1 CTF4 CYS4 DBP10 DCP1 DCP2 DED81 DIA2 DIM1 DNM1 DOG1 DPS1 EDC3 EDE1 EGD2 ENP1 ERG10 ERG20 FAA1 FET4 FPR3 GAR1 GAS1 GCN3 GLC7 GPH1 GRS1 GSP1 GSP2 HAS1 HEM15 HHF1, HHF2 HRP1 HRR25 HSP104 HTA2 HXT7 HYP2 ILS1 IPP1 KAP104 KRE33 KRI1 KTR3 LOC1 LPD1 LSP1 LST4 LTV1 MAM33 MCM2 MCM3 MCM5 MDH1 MDS3 MGE1 MPC54 MRT4 NAB2 NAS6 NDE1 NIP7 NMD3 NOP12 NSA1 NUG1 OAC1 OYE2 PAA1 PDC5 PET10 PET9 PEX19 PGM2 PIL1 PIM1 PIN4 PRP8 PSD1 PTC4 PUF3 QCR2 RIO2 RPC19 RPM2 RPT4 RRP12 RTN2 SAC1 SAP185 SAP190 SAS10 SEC2 SEC23 SEH1 SES1 SFB3 SGM1 SIT4 SKP1 SLT2 SNP1 SPB1 SRP1 SSF1 SSF2 SSZ1 SUI1 TFG2 TGL1 THR4 TIF6 TMA19 TPS1 TRR1 TSR1 URB1 UTP10 VAC14 VMA4 VMA8 YAK1 YBL104C YBR225W YDL063C YDL124W YER138C YHM2 YNL035C YRB1
    View Details Qiu et al. (2008) BRX1 BUD21 DBP6 DBP7 DIP2 ENP1 FPR4 GAR1 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MRD1 NAN1 NOB1 NOC2 NOC3 NOC4 NOP14 NSA1 NSR1 NUG1 PWP2 PXR1 RRP1 RRP5 RRP9 SBP1 SOF1 UTP10 UTP11 UTP13 UTP14 UTP15 UTP20 UTP21 UTP22 UTP4 UTP5 UTP6 UTP7 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen TPP1 ENP1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ENP1 Huh WK, et al. (2003)
    View Data ENP1 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] MSA 1.008981 View MSA. No confident structure predictions are available.
    2 View Details [183..328] MSA 1.008977 View MSA. No confident structure predictions are available.
    3 View Details [329..483] MSA 1.007957 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle