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Protein Overview: GAR1

General Information:
Name(s) found: GAR1 / YHR089C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: box H/ACA snoRNP complex [IPILink to PubMed article]
    nuclear outer membrane [TASLink to PubMed article]
    nucleolus [IDALink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: RNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRGGNRGG RGGFRGGFRG GRTGSARSFQ QGPPDTVLEM GAFLHPCEGD IVCRSINTKI  60
   61 PYFNAPIYLE NKTQVGKVDE ILGPLNEVFF TIKCGDGVQA TSFKEGDKFY IAADKLLPIE 120
  121 RFLPKPKVVG PPKPKNKKKR SGAPGGRGGA SMGRGGSRGG FRGGRGGSSF RGGRGGSSFR 180
  181 GGSRGGSFRG GSRGGSRGGF RGGRR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GAR1 KRI1 NHP2 NOP10 NOP56 NOP58 RPF2 RPL4A RPL5 RPS16B, RPS16A RRP5 YGR283C
    View Details (MIPS) Mewes HW, et al. (2004) DRS1 GAR1 IFH1 NOP1 NPL3 NSR1 POP1 POP2 RAT1 RNT1 RRP3 SBP1 SNM1 SRD1 UTP10 UTP11 UTP13 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9 YME2
    View Details Krogan NJ, et al. (2006) COQ10 DBP3 DSE4 GAR1 KRI1 KRR1 NHP2 NOP10 NOP6 YCR016W YDR381C-A
    View Details Gavin AC, et al. (2002) AAR2 BRX1 CBF5 CIC1 DBP9 DRS1 ERB1 FUN12 GAR1 HAS1 KRE33 KRR1 LHP1 MAK21 MDN1 MIS1 MRP7 NHP2 NIP1 NOC2 NOG1 NOP1 NOP12 NOP2 NOP4 NOP56 NOP6 NOP7 NUG1 POL2 PRP4 PUF6 RLP7 RRP12 SMB1 SNU114 SNU66 SRO9 TIF4631 TIF4632 URB1 UTP10 UTP20 UTP21 YMR310C YTM1
    View Details Ho Y, et al. (2002) ADR1 APA1 AYR1 BGL2 BRX1 CBP6 CKB1 COX6 ENP1 FAA1 FET4 GAR1 GSP1 HEM15 HRP1 KAP104 KTR3 LSM2 LSM8 MRT4 NAB2 NDE1 NIP7 NMD3 NOC2 NOP1 NOP2 NOP56 NOP7 NSA1 NSA2 NUG1 OAC1 PET10 PET9 PHO84 PSD1 QCR2 RPN12 RPN8 RPT4 RRP1 RRP42 RTN2 SAC1 SMB1 TFG2 TIF6 VMA8 YDL063C YGL117W YHM2 YNL035C YPL009C
    View Details Qiu et al. (2008) BFR2 BRX1 BUD21 CIC1 DBP3 DBP7 DBP8 DHR2 DIP2 DRS1 ECM16 ENP1 ERB1 ESF1 ESF2 FPR3 FPR4 GAR1 HAS1 HCA4 IFH1 IMP3 JIP5 KRE33 KRI1 KRR1 LCP5 MAK5 MRT4 MTR4 NAN1 NHP2 NOC3 NOP1 NOP12 NOP13 NOP15 NOP2 NOP4 NOP56 NOP7 NOP8 NSA1 NSR1 NUG1 POP1 PRP43 PUF6 PWP2 PXR1 RAT1 RCL1 RNT1 RPF2 RPL15B RPL27A RPL7B RRP1 RRP3 RRP5 RRP9 SBP1 SNM1 SOF1 SPB4 SSF1 TIF6 URB1 URB2 UTP10 UTP11 UTP13 UTP14 UTP15 UTP18 UTP20 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NAF1 No Comments Hazbun TR, et al. (2003)
    View Run NOP9 No Comments Hazbun TR, et al. (2003)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run BOI2 Boi 2 gst control McCusker D, et al (2007)
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #08 Alpha Factor Prep4-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GAR1 and NOP56 Huh WK, et al. (2003)
    View Data GAR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] MSA 6.009975 View MSA. No confident structure predictions are available.
    2 View Details [131..205] ORFEUS 8.4 No description for 1la5A was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle