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Protein Overview: YDL063C

General Information:
Name(s) found: YDL063C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRSKKRSRA SSSRLNPLRK AGSNDNNKDT NVVNKKLQPL LQNLSSVVPN DRSIALSSIS  60
   61 VLCEDAHMRQ LLLKEKLVPI ILNKLLNDSN SDIVVESFGL LRNLSLEEGY DVSIYLWRSD 120
  121 IWTSITSNFG RIVESLSALQ AAEQQPQLKP AGKSKIESKR LLFDFADNLL SLVVALSNGS 180
  181 DDILNEILTE SKINEIFQVI SQLLKYGVEK LPINLFNTTL DLIYDLSSES FEFIDHVSNN 240
  241 ELLSQFLNGL SPALHPQANE LTKVLIEGIH CQFLDMKITY DQCNKMIHSV CHSINNIDPV 300
  301 QLVNDINNPV EIGPATSKDE SSKVITKIKD YNAKRNESMI KLQSIEIAID LITAIIEIVA 360
  361 SKYESPESQE VAIPEELINT LTNFLPHVFM ILKDTFTSRI LIGWNNLIWL FVSLSLTELS 420
  421 GELLTTLWSY VTQLDSQDDL SIKIGRMGCI WALLKLIFPD GAFESENRAL INVQMLNNSG 480
  481 FARGIIEEFQ NNNDLELQQK CINVLSTYAM IQGQIDANKE IGQFFIQTLT QLNVRPEILI 540
  541 EMTNSLFQIY GDASYDYNEP IFVRGGFLSI LKDQVVPNLR QQFKMVDKNK NPELKERCHD 600
  601 CFTTLDSFIH YKMNENSTNQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADR1 AYR1 BGL2 CBP6 DPS1 ENP1 FAA1 GAR1 GSP1 GSP2 HEM15 HRP1 KAP104 KTR3 MRT4 NAB2 NDE1 OAC1 PET10 PET9 PGM2 PSD1 RPT4 RTN2 SAC1 TFG2 VMA8 YDL063C YHM2 YNL035C YRB1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YDL063C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] ORFEUS 8.73 Importin beta
    2 View Details [204..312] ORFEUS 8.73 Importin beta
    3 View Details [313..620] ORFEUS 8.73 Importin beta


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle