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Protein Overview: FET4

General Information:
Name(s) found: FET4 / YMR319C [SGD]
Description(s) found:
Found 21 descriptions.
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  • Low-affinity Fe(II) transporter of the plasma membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: low-affinity iron ion transport [IMPLink to PubMed article]
    intracellular copper ion transport [IMPLink to PubMed article]
    copper ion import [IMPLink to PubMed article]
    Molecular Function: iron ion transmembrane transporter activity [IMPLink to PubMed article]
    copper ion transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKIAEFLGN PGARPDVHHR APTVDCKQYE EFGDSNDYKN DDVVRVVSHS DESTDDELCN  60
   61 VNLTETGAIF TSKGFTGLSK GFTDKTLDFL VRVAGSQAVF FIVWIILIIW VVIGIVYNAP 120
  121 FNWQVVMQDG QSIQSYVWDT LLMRQQLMST HEQILICGRL KSRLASFKNY LTRSTPEEEK 180
  181 ADCTVEANEV SSVENHIDPS AINGELPVEN WYDRLSNVAS RYMGSIAAMV IFWIGIFVWI 240
  241 GCGAIPKDAG NTPPYTGETT GSNPRLKKFS DAWQMYINTA VAVSLLICTT FLQNIRARHD 300
  301 YFTGRFLVDI FDMDEKIDYR IRKHFNDFET PHPVVTIESK KRSTGRKMID WYADIIGTGI 360
  361 GVLIGVAVFA TWIGIGSPMK WDDNWWLIIG TYTGLIGFLD GFVLREVYFR IVQHEEKNYS 420
  421 DVAKEDLELF QELGIECPEE FSGKAPEINT IGYRTSQYIN RICSTPWSVL VSVIIIIGLI 480
  481 CIASGLRWST TGQLIANTPT MIIEEFFLLV LLQAHNWADR QRRVEVTALY ARRRILLSYV 540
  541 EKRFPEVMML EK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FET4 PHO84
    View Details Ho Y, et al. (2002) AAC1 AAC3 ADA2 ADE5,7 ADK1 AHA1 AIM46 ARC1 ARE1 ARO1 ARP10 ARP2 ARP7 ATG11 ATG12 ATG17 AVO1 BCP1 BCY1 BFA1 BRX1 CAR2 CDC33 CKB1 COR1 COX6 CPA2 CPR6 DIG1 DIG2 DIP2 DIP5 DOG1 ENP1 FAR10 FAR7 FAR8 FET4 FPR3 FUN12 GAR1 GCD11 GCN5 GFA1 GRS1 GUS1 HAS1 HFI1 HHF1, HHF2 HOG1 HXT6 HXT7 IMD2 IMD3 IMD4 IPP1 KEX2 KRE33 KRI1 KSS1 LSP1 MAG2 MAM33 MGM101 MKT1 MSC3 MSE1 MUM2 NAP1 NIP7 NMD3 NOC2 NOP1 NOP12 NOP2 NOP4 NOP56 NOP7 NPL3 NSA1 NSA2 NUG1 OYE2 PBS2 PDC6 PGM2 PHO84 PIL1 PIM1 PMA1 POR1 PPX1 PRB1 PRP8 PTC7 PTP3 PYC1 QCR2 RCK2 REP1 REX2 RGC1 RIM15 RKM1 RPA135 RPF2 RPL23B, RPL23A RPN10 RPN11 RPN3 RPN5 RPN6 RPN7 RPT1 RPT3 RRP1 RRP12 RRP5 SAP185 SAP190 SEC18 SEN1 SES1 SGF29 SIT4 SNP1 SPT7 SRP1 SRV2 SSK2 STE12 STE23 STE7 TAF6 TCB1 TCP1 TEC1 TFP1 TIF1, TIF2 TIF4631 TIF4632 TPK1 TPK2 TPK3 TRA1 TYR1 UBI4 UBP8 UTP13 UTP18 UTP22 VAC14 VPS13 VPS64 YBL036C YDR239C YHR020W YHR033W YNL208W YPL009C
    View Details Qiu et al. (2008) CTR3 FET3 FET4 ZRT1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FET4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] ORFEUS 8.46 Monomeric isocitrate dehydrogenase
    2 View Details [190..329] ORFEUS 8.46 Monomeric isocitrate dehydrogenase
    3 View Details [330..552] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle