Protein Overview: FAR10

General Information:
Name(s) found:	FAR10 / YLR238W [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate [SGD]
Organism:	Saccharomyces cerevisiae
Length:	478 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	cell cycle arrest in response to pheromone [IMP][IPI]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGPGPEINK EEHPSSPGKK QITYNSIPKN ANLIDGSTNS SKRPIEKYDK RIADPTKSYF  60
   61 PHSISRTPRR KYTYILVLTS LNGTFESKHV VIPFKPDGLK LGRPVANSNS SSSSSLRGGK 120
  121 RVDSHTFSQV RSDNGNFDSR VLSRNHALLS CDPLTGKVYI RDLKSSNGTF INGQRIGSND 180
  181 VEIKVGDVID LGTDIDTKIE HRKISATVEE LFVQPLLESP IFENEDSDDC HTITEKEEAA 240
  241 AITSHIYGDS NNLELEEVIL GSDTEILSGI FINNCIGTSP TLSNIIKTLA MEIPFSKCDN 300
  301 FKLQSMENFL INYTTHLEYT NKLLVEKNDQ QLVKLQNGLR RKLSGKYEKI IEQNRNQVKQ 360
  361 LERDHMFFKK SFEVKKRRNN EKQKSMEREI EDLKTRLEVE RYKNSQMMKK NKQKEQELST 420
  421 ASKKKTTEHD TRGVPGMNPK GTDKFSIKNT LCNHFTLLTF GTISIGIIAI VFKILSPN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		FAR10 FAR8 FET4 PHO84

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	FAR10	VPS64	2	Uetz P, et al. (2000)
View Screen	FAR10	ROX3	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..112]	deduced	N/A	No confident structure predictions are available.
2	View Details	[113..478]	PSI-BLAST	17.69897	Heavy meromyosin subfragment

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2