YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: RPN7

General Information:
Name(s) found: RPN7 / YPR108W [SGD]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 429 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle, lid subcomplex [IPILink to PubMed article]
    Biological Process: ubiquitin-dependent protein catabolic process [TASLink to PubMed articleLink to PubMed article]
    Molecular Function: structural molecule activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDVEEKSQE VEYVDPTVNR VPNYEVSEKA FLLTQSKVSI EQRKEAAEFV LAKIKEEEMA  60
   61 PYYKYLCEEY LVNNGQSDLE HDEKSDSLNE WIKFDQELYN ELCKKNESKI KELNEKIQKL 120
  121 EEDDEGELEQ AQAWINLGEY YAQIGDKDNA EKTLGKSLSK AISTGAKIDV MLTIARLGFF 180
  181 YNDQLYVKEK LEAVNSMIEK GGDWERRNRY KTYYGIHCLA VRNFKEAAKL LVDSLATFTS 240
  241 IELTSYESIA TYASVTGLFT LERTDLKSKV IDSPELLSLI STTAALQSIS SLTISLYASD 300
  301 YASYFPYLLE TYANVLIPCK YLNRHADFFV REMRRKVYAQ LLESYKTLSL KSMASAFGVS 360
  361 VAFLDNDLGK FIPNKQLNCV IDRVNGIVET NRPDNKNAQY HLLVKQGDGL LTKLQKYGAA 420
  421 VRLTGSDRV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) DBF4 ECM29 NAS6 OSH7 PRE5 RPN1 RPN10 RPN11 RPN12 RPN13 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SEC18 SEM1 SPG5 UBP6 URA3
    View Details (MIPS) Mewes HW, et al. (2004) NAS6 RPN1 RPN10 RPN11 RPN12 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6
    View Details Krogan NJ, et al. (2006) CSI1 CSN9 ERV46 FPR2 HUL5 IQG1 MOT1 MPT5 NAS6 NMD3 NPT1 PCI8 PEP1 PST1 PUS9 RPN1 RPN10 RPN11 RPN12 RPN13 RPN14 RPN2 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 RRI1 RRI2 SEC18 SEM1 SKP1 SPG5 SPO77 SQT1 SWA2 TCB2 TIP41 TOD6 TOR2 TSR4 UBP6 YEN1 YKL027W YMR258C YNL022C YPR003C YPT52
    View Details Gavin AC, et al. (2006) ECM29 RPN1 RPN10 RPN11 RPN12 RPN13 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1
    View Details Gavin AC, et al. (2002) BLM10 CDC6 ECM29 GFA1 MLH2 NAS6 PGK1 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP3 RGR1 RPN10 RPN11 RPN12 RPN13 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SCL1 UBP6 YFL006W
    View Details Ho Y, et al. (2002) AAC1 AAC3 ADE5,7 AHA1 ARC1 ARO1 ARP2 ATG11 ATG12 ATG17 BCK1 BTN2 BUL1 CAR2 CCT2 CCT6 CMD1 CMP2 COP1 CPA2 CPR6 CTR1 DHH1 EAP1 FET4 GAL7 GCD11 GDT1 GFA1 GUS1 IDH1 IDH2 IPP1 LHS1 LYS12 MDN1 MEH1 MKK2 MKT1 NAS6 NPA3 PPX1 PRB1 PTC7 REP1 REX2 RFC3 RGD1 RNQ1 RPN1 RPN10 RPN11 RPN12 RPN13 RPN14 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RVB1 SEC18 SEC27 SEC28 STI1 TCB1 TCP1 TEF4 TIF1, TIF2 TYR1 UBC12 YCR076C YHR020W YHR033W YNL208W
    View Details Qiu et al. (2008) NAS6 PRE10 PRE6 RPN1 RPN10 RPN11 RPN12 RPN13 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SGT1 RPN7 2 Unpublished Fields Lab Data
    View Screen SGT1 RPN7 2 Unpublished Fields Lab Data
    View Screen SGT1 RPN7 2 Unpublished Fields Lab Data
    View Screen SGT1 RPN7 2 Unpublished Fields Lab Data
    View Screen RPN7 SNA4 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RPN7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] MSA 1.165995 View MSA. No confident structure predictions are available.
    2 View Details [91..271] PSI-BLAST 5.39794 Designed protein cTPR3
    3 View Details [272..429] MSA 10.215994 View MSA. No confident structure predictions are available.
    4 View Details [319..429] PSI-BLAST 11.045757 Solution structure of the PCI domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle