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Protein Overview: BTN2

General Information:
Name(s) found: BTN2 / YGR142W [SGD]
Description(s) found:
Found 26 descriptions.
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  • v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: late endosome [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: intracellular protein transport [IMPLink to PubMed article][IPILink to PubMed article]
    retrograde transport, endosome to Golgi [IMPLink to PubMed article]
    amino acid transport [IMPLink to PubMed article]
    regulation of pH [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSIFNSPCV FEQLPSFSQP LHSRYFDCSS PVSYYPECKR RKAIKANLRA PKKSDANCSE  60
   61 PLRYALAETP NGYTLSLSKR IPYELFSKYV NEKLGELKEN HYRPTYHVVQ DFFGNQYYVE 120
  121 DEADEDALLR SALKDLDFRA IGKKIAKDLF QDYEIELNHR GDELSILSKK DKIFKEFSLD 180
  181 QVFEDVFVIG CGVENIDDGS REKYALLKIG LVKHEEEISE GGINEPKMPI IESKIDESHD 240
  241 DVNMSESLKE EEAEKAKEPL TKEDQIKKWI EEERLMQEES RKSEQEKAAK EDEERQKKEK 300
  301 EARLKARKES LINKQKTKRS QQKKLQNSKS LPISEIEASN KNNNSNSGSA ESDNESINSD 360
  361 SDTTLDFSVS GNTLKKHASP LLEDVEDEEV DRYNESLSRS PKGNSIIEEI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BTN2 YMR144W
    View Details Ho Y, et al. (2002) BTN2 CCT2 CCT6 COP1 CTR1 DHH1 EAP1 GAL7 GDT1 IDH1 MEH1 PRB1 RPN7 RPT3 SEC27 SEC28 STI1 TCP1 YCR076C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BTN2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..410] PSI-BLAST 5.0 Heavy meromyosin subfragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle