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Protein Overview: GDT1

General Information:
Name(s) found: GDT1 / YBR187W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL  60
   61 IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 120
  121 TMEGLEMSKD AGVEEEMAEV EEEIAIKDMN QDMDDVEKGG DTAYDKQLKN ASIGKKIVHR 180
  181 IRELASFMFS PVWVQIFLMV FLGELGDRSQ ISIIAMATDS DYWYVIAGAV IGHAICSGLA 240
  241 VVGGKLLATR ISIRTITLAS SLLFFIFALM YIYQAFTTQD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GDT1 MRD1 NOP12 RRP17
    View Details Ho Y, et al. (2002) BTN2 CCT2 CCT6 COP1 CTR1 DHH1 EAP1 GAL7 GDT1 IDH1 MEH1 PRB1 RPN7 RPT3 SEC27 SEC28 STI1 TCP1 YCR076C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GDT1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] Pfam 39.0 Uncharacterized protein family UPF0016 Confident ab initio structure predictions are available.
    2 View Details [128..188] deduced N/A No confident structure predictions are available.
    3 View Details [189..280] Pfam 42.823909 Uncharacterized protein family UPF0016 Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle