YRC Public Data Repository - Protein Structure Prediction

Protein:	GDT1
Organism:	Saccharomyces cerevisiae
Length:	280 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDT1.

Description	E-value	Query Range	Subject Range
gi\|7689027 - gi\|7689027\|gb\|AAF67653.1\|AF220188_1 uncharacterized hypothalamus protein HTMP [Homo sapiens]	311.0	[0..9]	[273..59]
gi\|76619924 - gi\|76619924\|ref\|XP_611725.2\| PREDICTED: similar to transmembrane protein 165 [Bos taurus]	309.0	[0..8]	[273..58]
gi\|73975293 - gi\|73975293\|ref\|XP_532375.2\| PREDICTED: similar to TPA regulated locus [Canis familiaris]	307.0	[0..8]	[273..59]
gi\|109074795 - gi\|109074795\|ref\|XP_001088728.1\| PREDICTED: similar to TPA regulated locus isoform 3 [Macaca mulatta...	300.0	[0..14]	[273..71]
gi\|50747071 - gi\|50747071\|ref\|XP_426336.1\| PREDICTED: similar to TPA regulated locus; uncharacterized hypothalamus...	300.0	[0..19]	[273..132]
TM165_MOUSE - Transmembrane protein 165 OS=Mus musculus GN=Tmem165 PE=1 SV=2	295.0	[0..8]	[273..58]
TM165_RAT - Transmembrane protein 165 OS=Rattus norvegicus GN=Tmem165 PE=2 SV=1	292.0	[0..8]	[273..58]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL  60
   61 IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 120
  121 TMEGLEM

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	39.0
Match:	PF01169
Description:	Uncharacterized protein family UPF0016

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.978	N/A	N/A	a.7.8	GAT domain

Predicted Domain #2

Region A:
Residues: [128-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKDAGVEEEM AEVEEEIAIK DMNQDMDDVE KGGDTAYDKQ LKNASIGKKI VHRIRELASF  60
   61 M

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [189-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSPVWVQIFL MVFLGELGDR SQISIIAMAT DSDYWYVIAG AVIGHAICSG LAVVGGKLLA  60
   61 TRISIRTITL ASSLLFFIFA LMYIYQAFTT QD

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	42.823909
Match:	PF01169
Description:	Uncharacterized protein family UPF0016

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.892	N/A	N/A	a.7.2	Enzyme IIa from lactose specific PTS, IIa-lac

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits