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View Structure Prediction Details

Protein: GDT1
Organism: Saccharomyces cerevisiae
Length: 280 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDT1.

Description E-value Query
Range
Subject
Range
gi|7689027 - gi|7689027|gb|AAF67653.1|AF220188_1 uncharacterized hypothalamus protein HTMP [Homo sapiens]
311.0 [0..9] [273..59]
gi|76619924 - gi|76619924|ref|XP_611725.2| PREDICTED: similar to transmembrane protein 165 [Bos taurus]
309.0 [0..8] [273..58]
gi|73975293 - gi|73975293|ref|XP_532375.2| PREDICTED: similar to TPA regulated locus [Canis familiaris]
307.0 [0..8] [273..59]
gi|109074795 - gi|109074795|ref|XP_001088728.1| PREDICTED: similar to TPA regulated locus isoform 3 [Macaca mulatta...
300.0 [0..14] [273..71]
gi|50747071 - gi|50747071|ref|XP_426336.1| PREDICTED: similar to TPA regulated locus; uncharacterized hypothalamus...
300.0 [0..19] [273..132]
TM165_MOUSE - Transmembrane protein 165 OS=Mus musculus GN=Tmem165 PE=1 SV=2
295.0 [0..8] [273..58]
TM165_RAT - Transmembrane protein 165 OS=Rattus norvegicus GN=Tmem165 PE=2 SV=1
292.0 [0..8] [273..58]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL  60
   61 IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 120
  121 TMEGLEM

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 39.0
Match: PF01169
Description: Uncharacterized protein family UPF0016

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.978 N/A N/A a.7.8 GAT domain
View Download 0.905 N/A N/A a.7.8 GAT domain
View Download 0.808 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.799 N/A N/A a.24.26 Description not found.
View Download 0.787 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.787 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.736 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.724 N/A N/A a.25.1 Ferritin-like
View Download 0.691 N/A N/A a.25.1 Ferritin-like
View Download 0.677 N/A N/A a.25.1 Ferritin-like

Predicted Domain #2
Region A:
Residues: [128-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKDAGVEEEM AEVEEEIAIK DMNQDMDDVE KGGDTAYDKQ LKNASIGKKI VHRIRELASF  60
   61 M

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.767 a.159.2 FF domain
View Download 0.721 a.4.1 Homeodomain-like
View Download 0.721 a.4.1 Homeodomain-like
View Download 0.714 a.4.1 Homeodomain-like
View Download 0.714 a.4.1 Homeodomain-like
View Download 0.702 a.159.2 FF domain
View Download 0.685 a.4.1 Homeodomain-like
View Download 0.657 a.4.1 Homeodomain-like

Predicted Domain #3
Region A:
Residues: [189-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSPVWVQIFL MVFLGELGDR SQISIIAMAT DSDYWYVIAG AVIGHAICSG LAVVGGKLLA  60
   61 TRISIRTITL ASSLLFFIFA LMYIYQAFTT QD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 42.823909
Match: PF01169
Description: Uncharacterized protein family UPF0016

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.892 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.892 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.887 N/A N/A a.7.8 GAT domain
View Download 0.876 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.876 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.872 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.872 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.866 N/A N/A a.7.8 GAT domain
View Download 0.866 N/A N/A a.7.8 GAT domain
View Download 0.860 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle