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Protein Overview: UTP9

General Information:
Name(s) found: UTP9 / YHR196W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 575 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: maturation of SSU-rRNA [IMPLink to PubMed article][IPILink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: snoRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSLDLVAS FSHDSTRFAF QASVAQKNNV DIYPLNETKD YVVNSSLVSH IDYETNDMKV  60
   61 SDVIFFGWCS DLIDTQSSNI KRKLDEDEGT GESSEQRCEN FFVNGFPDGR IVVYSSNGKD 120
  121 IVNIIKNKKE ILGADTDESD IWILDSDKVV KKLQYNNSKP LKTFTLVDGK DDEIVHFQIL 180
  181 HQNGTLLVCI ITKQMVYIVD PSKRRPSTKY SFEISDAVAC EFSSDGKYLL IANNEELIAY 240
  241 DLKEDSKLIQ SWPVQVKTLK TLDDLIMALT TDGKINNYKI GEADKVCSIV VNEDLEIIDF 300
  301 TPINSKQQVL ISWLNVNEPN FESISLKEIE TQGYITINKN EKNNADEADQ KKLEEKEEEA 360
  361 QPEVQHEKKE TETKINKKVS KSDQVEIANI LSSHLEANST EILDDLMSGS WTEPEIKKFI 420
  421 LTKINTVDHL SKIFLTISKS ITQNPWNEEN LLPLWLKWLL TLKSGELNSI KDKHTKKNCK 480
  481 HLKSALRSSE EILPVLLGIQ GRLEMLRRQA KLREDLAQLS MQEGEDDEIE VIEHSNVISN 540
  541 PLQDQASPVE KLEPDSIVYA NGESDEFVDA SEYKD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) EMG1 IMP3 MPP10 NAN1 NOC4 OKP1 POL5 SOF1 UTP10 UTP15 UTP4 UTP5 UTP7 UTP8 UTP9
    View Details Hazbun TR, et al. (2003) BFR2 ENP2 ESF1 HCA4 LCP5 NOP58 UTP9
    View Details (MIPS) Mewes HW, et al. (2004) DRS1 GAR1 IFH1 NOP1 NPL3 NSR1 POP1 POP2 RAT1 RNT1 RRP3 SBP1 SNM1 SRD1 UTP10 UTP11 UTP13 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9 YME2
    View Details Krogan NJ, et al. (2006) GFD2 NAN1 POL5 UTP10 UTP15 UTP4 UTP5 UTP8 UTP9
    View Details Gavin AC, et al. (2006) CMS1 DIP2 MRD1 NAN1 NOP58 PNO1 PWP2 ROK1 RRP9 UTP10 UTP13 UTP15 UTP18 UTP21 UTP22 UTP4 UTP6 UTP7 UTP8 UTP9
    View Details Gavin AC, et al. (2002) ADE4 ASC1 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SOF1 SRO9 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YOR059C YSH1
    View Details Ho Y, et al. (2002) GND1 GPH1 HSP104 KGD1 NAN1 PFK1 SCS2 TPS2 UTP10 UTP9
    View Details Qiu et al. (2008) BFR2 BUD21 BUD22 DBP3 DBP7 DBP8 DHR2 DIP2 DRS1 ENP1 ERB1 ESF1 ESF2 FCF2 FOB1 GAR1 HCA4 IFH1 IMP3 IMP4 JIP5 KRI1 KRR1 MAK11 MAK5 MRD1 MRT4 MTR4 NAN1 NOC2 NOC3 NOP12 NOP13 NOP14 NOP15 NOP4 NOP7 NOP8 NSA1 NSR1 NUG1 POP1 PUF6 PWP1 PWP2 PXR1 RCL1 RNT1 RRP1 RRP3 RRP5 RRP9 SAS10 SBP1 SGD1 SOF1 SPB4 SSF1 URB1 URB2 UTP10 UTP11 UTP13 UTP14 UTP15 UTP18 UTP20 UTP21 UTP22 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ESF1 No Comments Hazbun TR, et al. (2003)
    View Run ESF1 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UTP9 Unpublished Data
    View Data UTP9 and NOP56 Huh WK, et al. (2003)
    View Data UTP9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..369] Pcons 1.54 beta1-subunit of the signal-transducing G protein heterotrimer
    2 View Details [370..443] Pcons 1.64 Tup1, C-terminal domain
    3 View Details [444..575] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
    		• 3.17730118508639 bayes_pls_golite062009
  • snoRNA binding
    		•  3.12844073350845 bayes_pls_golite062009
  • RNA binding
    		•  2.97000647761702 bayes_pls_golite062009
  • binding
    		•  2.38386546684697 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36560618519891 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30172153305516 bayes_pls_golite062009
  • protein binding
    		•  2.19549049361621 bayes_pls_golite062009
  • DNA binding
    		•  1.74970945772818 bayes_pls_golite062009
  • structural molecule activity
    		•  1.32884088690898 bayes_pls_golite062009
  • transcription activator activity
    		•  1.24665557926829 bayes_pls_golite062009
  • transcription factor activity
    		•  1.10790917305704 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.561205988591905 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.435475723571992 bayes_pls_golite062009
  • transcription factor binding
    		•  0.421428497325728 bayes_pls_golite062009
  • ligase activity
    		•  0.279385134085056 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.203779337313278 bayes_pls_golite062009
  • mRNA binding
    		•  0.0554986997005726 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.00328955300255629 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle