YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MAK11

General Information:
Name(s) found: MAK11 / YKL021C [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    Biological Process: ribosomal large subunit biogenesis [IMPLink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    ribosomal large subunit assembly [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    processing of 27S pre-rRNA [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLNTTYTVF IFFLLRIIKF KIKAENFLEH EKLKTHGTSS RKDPKGQVKN SCRKMSAIGD  60
   61 KNQFRIIVGS YEHNILCLSL DIPNQKENDA AKTPHFMPIF HFQAHSLSIK CLAVSRRYLV 120
  121 SGSNDEHIRI YDLQKRKELG TLLSHQGSIT ALQFSHPASS SEDAAVSKGS KNSKWLLSAS 180
  181 EDHKIMVWRV KDWETVGTLK GHTARVNDVD IHPTNRIAIS VSDDHSIRLW NLMTLRNAAV 240
  241 LKLRKYNTNG TCVRWLGAKG DYFAVGLRDR VLIYETGSAK VFKEIVFQRK TLMHIETHIL 300
  301 PFDNKEYLSV GISDGNVHFY PCEELFEKVE ENEKQEDDDD KEDISPAFSL LGHTNRIKDF 360
  361 KFYTNEFGTY LVTIGSDGKI VVWDMSTKEQ VAVYDCGERL NCLTLCDESI EKYNTMKKRD 420
  421 AETADIGDQS EVESDTEELK KIMFGEKKKL NKKKRKQLKK SKVSVELE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ERB1 HUL5 MAK11 NOP2 NOP7 TIF6
    View Details Qiu et al. (2008) BRX1 MAK11 NAN1 NOP15 NSR1 NUG1 PXR1 UTP15 UTP4 UTP5 UTP9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MAK11 and NOP56 Huh WK, et al. (2003)
    View Data MAK11 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] PSI-BLAST 100.512579 beta1-subunit of the signal-transducing G protein heterotrimer
    2 View Details [105..468] PSI-BLAST 122.035458 Tup1, C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle