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Protein Overview: BUD22

General Information:
Name(s) found: BUD22 / YMR014W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein that cosediments with pre-ribosomal particles, required for biogenesis of the small ribosomal subunit; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 519 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: cellular bud site selection [IMPLink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSESSVSIY KLDQLEYQYH YLTKSLQKFE PRYPKTAKLY NCIGKKNKKK IEKLLNSLEL  60
   61 KTLDKELDES YSKLLNNKIH YYETHLSKCI KEQIQKISKK NSSKVKDAQK NKSPSIDIEK 120
  121 MLATQLSLDD LALFMTRFRL IKILHQRIKQ KSKKIEGDTN NKTWLNNNDY SGYINDKTSK 180
  181 WNPSNIWNEV ITKLPSCEKL NALIGQSKIV QNLTESFDLS ICLIFGFDVS AMKAKKYGAR 240
  241 EKTANANQTH SNIDYDTDDG NEKNAIDSKS NAIGAQTQSN KETTSDNEDL LIKEYEGMLG 300
  301 SSGDEGEGGG YLNPNINYNE VTDEEPSEAS SDEDDSDERF SDSEENEPRR KKPKLHNLPE 360
  361 LMAGYYSGND TEEESDEDNK NVKGKKKKRD TAEDRTAREQ MSNEPKRKNR RGQRARRKIW 420
  421 EKKYGSQAKH VQRELEKEME DRKQRQIEYE ARVAKREAKA ASLEASRSRE REDRRTETNN 480
  481 KKEKESASTG EEHPSWIAKR LAEEKLQKAK FEGKKIKFD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BUD22 YGR272C
    View Details Krogan NJ, et al. (2006) BUD22 CIC1 DBP6 EFG1 FRE3 GIS2 HAS1 MAK21 NIP7 NOB1 NOC2 NOC3 NOP1 NOP2 NOP8 PUS7 RRP5 RSA3 SBP1 SFA1 SSQ1 YGR272C YMR034C YRF1-8, YRF1-5, ...
    View Details Qiu et al. (2008) BRX1 BUD22 DRS1 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BUD22 Huh WK, et al. (2003)
    View Data BUD22 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [111..236] MSA 5.077996 View MSA. No confident structure predictions are available.
    3 View Details [237..519] PSI-BLAST 5.09691 Heavy meromyosin subfragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle