YRC Public Data Repository - Protein Structure Prediction

Protein:	BUD22
Organism:	Saccharomyces cerevisiae
Length:	519 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUD22.

Description	E-value	Query Range	Subject Range
BUD22_YEAST - Bud site selection protein 22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD22 PE=1... gi\|151946175 - gi\|151946175\|gb\|EDN64406.1\| bud site selection protein [Saccharomyces cerevisiae YJM789] BUD22 - Protein that cosediments with pre-ribosomal particles, required for biogenesis of the small ribosoma...	0.0	[1..519]	[1..519]
gi\|17428053 - gi\|17428053\|emb\|CAD14742.1\| probable ribonuclease e (rnase e) protein [Ralstonia solanacearum GMI100... gi\|17545759 - gi\|17545759\|ref\|NP_519161.1\| ribonuclease E protein [Ralstonia solanacearum GMI1000]	2.0E-54	[107..492]	[347..746]
gi\|12659138 - gi\|12659138\|gb\|AAK01205.1\| mage-d3 [Mus musculus]	1.0E-48	[268..515]	[228..467]
CG13185-PB - This gene is referred to in FlyBase by the symbol Dmel\CG13185 (CG13185, FBgn0033661). It is a prote...	2.0E-38	[177..509]	[4568..4940]
gi\|13183005 - gi\|13183005\|gb\|AAK15023.1\| IgA1 protease [Neisseria meningitidis]	2.0E-38	[316..515]	[967..1166]
gi\|9558381, gi\|9... - gi\|9558384\|emb\|CAC00495.1\| initiation factor 2 [Streptococcus agalactiae], gi\|9558381\|emb\|CAC00493.1...	5.0E-36	[263..517]	[3..257]
gi\|11353751 - pir\|\|A81937 IgA-specific metalloendopeptidase (EC 3.4.24.13) NMA0905 [imported] - Neisseria meningit... gi\|121051831, gi... - gi\|7379617\|emb\|CAB84182.1\| IgA1 protease [Neisseria meningitidis Z2491], gi\|218767823\|ref\|YP_0023423...	3.0E-35	[316..504]	[966..1154]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSESSVSIY KLDQLEYQYH YLTKSLQKFE PRYPKTAKLY NCIGKKNKKK IEKLLNSLEL  60
   61 KTLDKELDES YSKLLNNKIH YYETHLSKCI KEQIQKISKK NSSKVKDAQK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.839	0.672	nucleus	a.29.2	Bromodomain

Predicted Domain #2

Region A:
Residues: [111-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSPSIDIEK MLATQLSLDD LALFMTRFRL IKILHQRIKQ KSKKIEGDTN NKTWLNNNDY  60
   61 SGYINDKTSK WNPSNIWNEV ITKLPSCEKL NALIGQSKIV QNLTESFDLS ICLIFGFDVS 120
  121 AMKAKK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [237-519]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGAREKTANA NQTHSNIDYD TDDGNEKNAI DSKSNAIGAQ TQSNKETTSD NEDLLIKEYE  60
   61 GMLGSSGDEG EGGGYLNPNI NYNEVTDEEP SEASSDEDDS DERFSDSEEN EPRRKKPKLH 120
  121 NLPELMAGYY SGNDTEEESD EDNKNVKGKK KKRDTAEDRT AREQMSNEPK RKNRRGQRAR 180
  181 RKIWEKKYGS QAKHVQRELE KEMEDRKQRQ IEYEARVAKR EAKAASLEAS RSREREDRRT 240
  241 ETNNKKEKES ASTGEEHPSW IAKRLAEEKL QKAKFEGKKI KFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.09691
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits