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View Structure Prediction Details

Protein: BUD22
Organism: Saccharomyces cerevisiae
Length: 519 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUD22.

Description E-value Query
Range
Subject
Range
BUD22_YEAST - Bud site selection protein 22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD22 PE=1...
gi|151946175 - gi|151946175|gb|EDN64406.1| bud site selection protein [Saccharomyces cerevisiae YJM789]
BUD22 - Protein that cosediments with pre-ribosomal particles, required for biogenesis of the small ribosoma...
0.0 [1..519] [1..519]
gi|17428053 - gi|17428053|emb|CAD14742.1| probable ribonuclease e (rnase e) protein [Ralstonia solanacearum GMI100...
gi|17545759 - gi|17545759|ref|NP_519161.1| ribonuclease E protein [Ralstonia solanacearum GMI1000]
2.0E-54 [107..492] [347..746]
gi|12659138 - gi|12659138|gb|AAK01205.1| mage-d3 [Mus musculus]
1.0E-48 [268..515] [228..467]
CG13185-PB - This gene is referred to in FlyBase by the symbol Dmel\CG13185 (CG13185, FBgn0033661). It is a prote...
2.0E-38 [177..509] [4568..4940]
gi|13183005 - gi|13183005|gb|AAK15023.1| IgA1 protease [Neisseria meningitidis]
2.0E-38 [316..515] [967..1166]
gi|9558381, gi|9... - gi|9558384|emb|CAC00495.1| initiation factor 2 [Streptococcus agalactiae], gi|9558381|emb|CAC00493.1...
5.0E-36 [263..517] [3..257]
gi|11353751 - pir||A81937 IgA-specific metalloendopeptidase (EC 3.4.24.13) NMA0905 [imported] - Neisseria meningit...
gi|121051831, gi... - gi|7379617|emb|CAB84182.1| IgA1 protease [Neisseria meningitidis Z2491], gi|218767823|ref|YP_0023423...
3.0E-35 [316..504] [966..1154]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSESSVSIY KLDQLEYQYH YLTKSLQKFE PRYPKTAKLY NCIGKKNKKK IEKLLNSLEL  60
   61 KTLDKELDES YSKLLNNKIH YYETHLSKCI KEQIQKISKK NSSKVKDAQK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.839 0.672 nucleus a.29.2 Bromodomain
View Download 0.839 0.672 nucleus a.29.2 Bromodomain
View Download 0.807 0.672 nucleus a.7.6 Ribosomal protein S20
View Download 0.750 0.672 nucleus f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.730 0.672 nucleus a.24.17 Group V grass pollen allergen
View Download 0.807 0.672 nucleus a.7.6 Ribosomal protein S20
View Download 0.789 0.672 nucleus a.7.6 Ribosomal protein S20
View Download 0.786 0.672 nucleus a.7.6 Ribosomal protein S20
View Download 0.765 0.672 nucleus a.7.6 Ribosomal protein S20
View Download 0.706 0.672 nucleus f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.688 0.672 nucleus a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.649 0.672 nucleus a.4.3 ARID-like
View Download 0.627 0.672 nucleus a.118.11 Cytochrome c oxidase subunit E
View Download 0.608 0.672 nucleus a.1.1 Globin-like
View Download 0.587 0.672 nucleus a.60.9 lambda integrase-like, N-terminal domain
View Download 0.561 0.672 nucleus a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.554 0.672 nucleus a.141.1 Frizzled cystein-rich domain
View Download 0.510 0.672 nucleus a.29.2 Bromodomain
View Download 0.495 0.672 nucleus a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.462 0.672 nucleus a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.458 0.672 nucleus d.15.6 Superantigen toxins, C-terminal domain
View Download 0.453 0.672 nucleus d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.449 0.672 nucleus a.61.1 Retroviral matrix proteins
View Download 0.442 0.672 nucleus f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.427 0.672 nucleus a.46.1 Methionine synthase domain
View Download 0.419 0.672 nucleus a.1.1 Globin-like
View Download 0.415 0.672 nucleus a.23.2 Diol dehydratase, gamma subunit
View Download 0.412 0.672 nucleus a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.409 0.672 nucleus a.142.1 PTS-regulatory domain, PRD
View Download 0.401 0.672 nucleus a.7.8 GAT domain
View Download 0.392 0.672 nucleus d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.374 0.672 nucleus a.4.5 "Winged helix" DNA-binding domain
View Download 0.371 0.672 nucleus d.21.1 Diaminopimelate epimerase-like
View Download 0.360 0.672 nucleus a.77.1 DEATH domain
View Download 0.353 0.672 nucleus a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.342 0.672 nucleus d.6.1 Prion-like
View Download 0.334 0.672 nucleus a.1.1 Globin-like
View Download 0.326 0.672 nucleus a.60.8 HRDC-like
View Download 0.324 0.672 nucleus a.85.1 Hemocyanin, N-terminal domain
View Download 0.323 0.672 nucleus a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.323 0.672 nucleus a.51.1 Cytochrome c oxidase subunit h
View Download 0.321 0.672 nucleus a.118.1 ARM repeat
View Download 0.319 0.672 nucleus a.1.1 Globin-like
View Download 0.316 0.672 nucleus a.7.1 Spectrin repeat
View Download 0.313 0.672 nucleus a.118.8 TPR-like
View Download 0.311 0.672 nucleus i.11.1 Computational models partly based on NMR data
View Download 0.311 0.672 nucleus d.54.1 Enolase N-terminal domain-like
View Download 0.309 0.672 nucleus f.14.1 Voltage-gated potassium channels
View Download 0.308 0.672 nucleus d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.300 0.672 nucleus d.26.1 FKBP-like
View Download 0.297 0.672 nucleus a.24.4 Hemerythrin
View Download 0.295 0.672 nucleus f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.286 0.672 nucleus d.134.1 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
View Download 0.284 0.672 nucleus c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.283 0.672 nucleus a.4.3 ARID-like
View Download 0.274 0.672 nucleus a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.271 0.672 nucleus a.7.1 Spectrin repeat
View Download 0.268 0.672 nucleus a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.267 0.672 nucleus a.1.1 Globin-like
View Download 0.266 0.672 nucleus a.1.1 Globin-like
View Download 0.265 0.672 nucleus a.126.1 Serum albumin-like
View Download 0.261 0.672 nucleus a.3.1 Cytochrome c
View Download 0.261 0.672 nucleus a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.259 0.672 nucleus d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.257 0.672 nucleus a.7.1 Spectrin repeat
View Download 0.257 0.672 nucleus a.69.2 Ypt/Rab-GAP domain of gyp1p
View Download 0.254 0.672 nucleus a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.253 0.672 nucleus a.118.8 TPR-like
View Download 0.253 0.672 nucleus a.26.1 4-helical cytokines
View Download 0.250 0.672 nucleus a.7.1 Spectrin repeat
View Download 0.249 0.672 nucleus c.47.1 Thioredoxin-like
View Download 0.248 0.672 nucleus a.25.1 Ferritin-like
View Download 0.247 0.672 nucleus a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.247 0.672 nucleus d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.247 0.672 nucleus d.110.4 SNARE-like
View Download 0.245 0.672 nucleus a.39.1 EF-hand
View Download 0.244 0.672 nucleus a.1.1 Globin-like
View Download 0.243 0.672 nucleus a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.243 0.672 nucleus d.232.1 Mago nashi protein
View Download 0.241 0.672 nucleus d.91.1 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
View Download 0.239 0.672 nucleus a.77.1 DEATH domain
View Download 0.238 0.672 nucleus a.24.3 Cytochromes
View Download 0.237 0.672 nucleus d.26.1 FKBP-like
View Download 0.232 0.672 nucleus d.58.49 YajQ-like
View Download 0.230 0.672 nucleus a.118.14 FliG
View Download 0.228 0.672 nucleus a.61.1 Retroviral matrix proteins
View Download 0.228 0.672 nucleus a.28.1 ACP-like
View Download 0.228 0.672 nucleus a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.227 0.672 nucleus a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.226 0.672 nucleus a.118.12 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View Download 0.226 0.672 nucleus a.77.1 DEATH domain
View Download 0.225 0.672 nucleus a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.221 0.672 nucleus a.4.5 "Winged helix" DNA-binding domain
View Download 0.219 0.672 nucleus d.8.1 Urease, gamma-subunit
View Download 0.219 0.672 nucleus a.118.9 ENTH/VHS domain
View Download 0.218 0.672 nucleus a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.218 0.672 nucleus d.58.26 GHMP Kinase, C-terminal domain
View Download 0.214 0.672 nucleus d.224.1 SufE-like
View Download 0.210 0.672 nucleus a.1.1 Globin-like
View Download 0.209 0.672 nucleus a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.208 0.672 nucleus a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.208 0.672 nucleus a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.207 0.672 nucleus f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.205 0.672 nucleus a.39.1 EF-hand
View Download 0.205 0.672 nucleus a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.205 0.672 nucleus a.25.1 Ferritin-like
View Download 0.203 0.672 nucleus a.47.2 t-snare proteins
View Download 0.203 0.672 nucleus d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.201 0.672 nucleus d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.200 0.672 nucleus c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.200 0.672 nucleus a.133.1 Phospholipase A2, PLA2

Predicted Domain #2
Region A:
Residues: [111-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSPSIDIEK MLATQLSLDD LALFMTRFRL IKILHQRIKQ KSKKIEGDTN NKTWLNNNDY  60
   61 SGYINDKTSK WNPSNIWNEV ITKLPSCEKL NALIGQSKIV QNLTESFDLS ICLIFGFDVS 120
  121 AMKAKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.553 0.298 nucleus a.25.1 Ferritin-like
View Download 0.320 0.169 nucleus a.90.1 Transcription factor STAT-4 N-domain
View Download 0.360 0.000 nucleus a.85.1 Hemocyanin, N-terminal domain
View Download 0.307 0.000 nucleus a.60.9 lambda integrase-like, N-terminal domain
View Download 0.301 N/A N/A a.25.1 Ferritin-like
View Download 0.288 N/A N/A d.26.1 FKBP-like
View Download 0.273 N/A N/A a.7.7 BAG domain
View Download 0.268 N/A N/A d.224.1 SufE-like
View Download 0.223 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.210 N/A N/A a.22.1 Histone-fold

Predicted Domain #3
Region A:
Residues: [237-519]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGAREKTANA NQTHSNIDYD TDDGNEKNAI DSKSNAIGAQ TQSNKETTSD NEDLLIKEYE  60
   61 GMLGSSGDEG EGGGYLNPNI NYNEVTDEEP SEASSDEDDS DERFSDSEEN EPRRKKPKLH 120
  121 NLPELMAGYY SGNDTEEESD EDNKNVKGKK KKRDTAEDRT AREQMSNEPK RKNRRGQRAR 180
  181 RKIWEKKYGS QAKHVQRELE KEMEDRKQRQ IEYEARVAKR EAKAASLEAS RSREREDRRT 240
  241 ETNNKKEKES ASTGEEHPSW IAKRLAEEKL QKAKFEGKKI KFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.09691
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle