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Protein Overview: YIL177C

General Information:
Name(s) found: YIL177C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Putative protein of unknown function; similarity to DNA helicases that are encoded within subtelomeric Y' elements and induced in telomerase deficient survivors [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1758 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: helicase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE KSGLIKVVKF  60
   61 RTGAMDRKRS FEKVVISVMV GKNVKKFLTF VEDEPDFQGG PIPSKYLIPK KINLMVYTLF 120
  121 QVHTLKFNRK DYDTLSLFYL NRGYYNELSF RVLERCHEIA SARPNDSSTM RTFTDFVSGA 180
  181 PIVRSLQKST IRKYGYNLAP YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK 240
  241 PIEIKYFSQI CNDMMNKKDR LGDILHIILR ACALNFGAGP RGGAGDEEDR SITNEEPIIP 300
  301 SVDEHGLKVC KLRSPNTPRR LRKTLDAVKA LLVSSCACTA RDLDIFDDNN GVAMWKWIKI 360
  361 LYHEVAQETT LKDSYRITLV PSSDGISLLA FAGPQRNVYV DDTTRRIQLY TDYNKNGSSE 420
  421 PRLKTLDGLT SDYVFYFVTV LRQMQICALG NSYDAFNHDP WMDVVGFEDP NQVTNRDISR 480
  481 IVLYSYMFLN TAKGCLVEYA TFRQYMRELP KNAPQKLNFR EMRQGLIALG RHCVGSRFET 540
  541 DLYESATSEL MANHSVQTGR NIYGVDSFSL TSVSGTTATL LQERASERWI QWLGLESDYH 600
  601 CSFSSTRNAE DVVAGEAASS NHHQKISRVT RKRPREPKST NDILVAGQKL FGSSFEFRDL 660
  661 HQLRLCYEIY MADTPSVAVQ APPGYGKTEL FHLPLIALAS KGDVEYVSFL FVPYTVLLAN 720
  721 CMIRLGRCGC LNVAPVRNFI EEGYDGVTDL YVGIYDDLAS TNFTDRIAAW ENIVECTFRT 780
  781 NNVKLGYLIV DEFHNFETEV YRQSQFGGIT NLDFDAFEKA IFLSGTAPEA VADAALQRIG 840
  841 LTGLAKKSMD INELKRSEDL SRGLSSYPTR MFNLIKEKSE VPLGHVHKIR KKVESQPEEA 900
  901 LKLLLALFES EPESKAIVVA STTNEVEELA CSWRKYFRVV WIHGKLGAAE KVSRTKEFVT 960
  961 DGSMQVLIGT KLVTEGIDIK QLMMVIMLDN RLNIIELIQG VGRLRDGGLC YLLSRKNSWA1020
 1021 ARNRKGELPP IKEGCITEQV REFYGLESKK GKKGQHVGCC GSRTDLSADT VELIERMDRL1080
 1081 AEKQATASMS IVALPSSFQE SNSSDRYRKY CSSDEDSNTC IHGSANASTN ASTNAITTAS1140
 1141 TNVRTNATTN ASTNATTNAS TNASTNATTN ASTNATTNSS TNATTTASTN VRTSATTTAS1200
 1201 INVRTSATTT ESTNSSTNAT TTESTNSSTN ATTTESTNSN TSATTTASIN VRTSATTTES1260
 1261 TNSSTSATTT ASINVRTSAT TTKSINSSTN ATTTESTNSN TNATTTESTN SSTNATTTES1320
 1321 TNSSTNATTT ESTNSNTSAA TTESTNSNTS ATTTESTNAS AKEDANKDGN AEDNRFHPVT1380
 1381 DINKESYKRK GSQMVLLERK KLKAQFPNTS ENMNVLQFLG FRSDEIKHLF LYGIDIYFCP1440
 1441 EGVFTQYGLC KGCQKMFELC VCWAGQKVSY RRIAWEALAV ERMLRNDEEY KEYLEDIEPY1500
 1501 HGDPVGYLKY FSVKRREIYS QIQRNYAWYL AITRRRETIS VLDSTRGKQG SQVFRMSGRQ1560
 1561 IKELYFKVWS NLRESKTEVL QYFLNWDEKK CQEEWEAKDD TVVVEALEKG GVFQRLRSMT1620
 1621 SAGLQGPQYV KLQFSRHHRQ LRSRYELSLG MHLRDQIALG VTPSKVPHWT AFLSMLIGLF1680
 1681 YNKTFRQKLE YLLEQISEVW LLPHWLDLAN VEVLAADDTR VPLYMLMVAV HKELDSDDVP1740
 1741 DGRFDILLCR DSSREVGE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARP7 ARP9 ATG16 CSH1 GRS2 HTL1 MGR1 NFI1 NPL6 PCL9 RIM15 RSC1 RSC2 RSC3 RSC4 RSC58 RSC6 RSC8 RSC9 RTT102 SFH1 STH1 URC2 YIL177C
    View Details Gavin AC, et al. (2002) CTR3 DAL3 GLN1 GTO3 IML1 MCM2 MKS1 REG1 TIF1, TIF2 TPS1 TPS2 TPS3 TSC10 TSL1 YIL177C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RIX1 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] MSA 2.009886 View MSA. No confident structure predictions are available.
    2 View Details [239..449] MSA 1.008927 View MSA. No confident structure predictions are available.
    3 View Details [450..557] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [558..1103] PSI-BLAST 158.228787 Initiation factor 4a
    5 View Details [1104..1464] ab initio 13.62 No description for 1m2vB was found.
    6 View Details [1465..1758] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle