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Protein Overview: RSM22

General Information:
Name(s) found: RSM22 / YKL155C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-dependent methyltransferase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 628 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial small ribosomal subunit [IDALink to PubMed article]
    Biological Process: translation [IDALink to PubMed article]
    Molecular Function: structural constituent of ribosome [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRCFSILP QNVRFSSKFT SLNLPKLDLA DFIDSNKRGI NVLPSYRDET ASTTQATNSK  60
   61 ELRLLSKTLQ GQSYRDQLEL NPDVSKAINN NIMAVHIPNN LRRVATNYYK EIQEPNSLHR 120
  121 PCRTKMEVDA HIASIFLQNY GSIFQSLKEL QKRVGPDNFK PQRILDVGYG PATGIVALND 180
  181 ILGPNYRPDL KDAVILGNAE MQERAKIILS RQLNEVVDTV EENVSTEKEQ ETDRRNKNFQ 240
  241 EDEHIGEVMT KKINIMTNLR SSIPASKEYD LIILTHQLLH DGNQFPIQVD ENIEHYLNIL 300
  301 APGGHIVIIE RGNPMGFEII ARARQITLRP ENFPDEFGKI PRPWSRGVTV RGKKDAELGN 360
  361 ISSNYFLKVI APCPHQRKCP LQVGNPNFYT HKEGKDLKFC NFQKSIKRPK FSIELKKGKL 420
  421 LATSWDGSQG NASRLKGTGR RNGRDYEILN YSYLIFERSH KDENTLKEIK KLRNENVNGK 480
  481 YDIGSLGDDT QNSWPRIIND PVKRKGHVMM DLCAPSGELE KWTVSRSFSK QIYHDARKSK 540
  541 KGDLWASAAK TQIKGLGDLN VKKFHKLEKE RIKQLKKEER QKARKAMESY NELEDSLQFD 600
  601 DHQFSNFEVM KKLSTFHGND FLQHVNRK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) EHD3 MRP1 MRP10 MRP13 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 SWS2
    View Details (MIPS) Mewes HW, et al. (2004) MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 VAR1 YMR31
    View Details Krogan NJ, et al. (2006) CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1
    View Details Gavin AC, et al. (2006) EHD3 MRP1 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM19 RSM22 RSM23 RSM25 RSM27 RSM7
    View Details Gavin AC, et al. (2002) BEM2 CCM1 ECM16 EHD3 FYV4 GEP3 HSC82 MRP1 MRP10 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PAP2 PET123 PSD2 PUS7 RIX1 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 TIF4631 UBP10 UTP20 UTP22
    View Details Qiu et al. (2008) EHD3 IMG1 MAM33 MRP1 MRP10 MRP13 MRP17 MRP2 MRP20 MRP21 MRP4 MRP49 MRP51 MRP7 MRP8 MRPL1 MRPL10 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL27 MRPL28 MRPL3 MRPL31 MRPL32 MRPL35 MRPL37 MRPL39 MRPL4 MRPL51 MRPL8 MRPL9 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 SWS2 VAR1 YML6 YMR31

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RSM22 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..491] MSA 3.011936 View MSA. No confident structure predictions are available.
    2 View Details [492..628] deduced N/A No confident structure predictions are available.
    3 View Details [396..548] MSA 2.063984 View MSA. No confident structure predictions are available.
    4 View Details [549..628] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  5.31568733625259 bayes_pls_golite062009
  • structural molecule activity
    		•  5.08906334129014 bayes_pls_golite062009
  • transcription factor activity
    		•  2.40166432224452 bayes_pls_golite062009
  • catalytic activity
    		•  1.16970557486814 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.06761237121162 bayes_pls_golite062009
  • transferase activity
    		•  0.822796502536128 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.797794853673959 bayes_pls_golite062009
  • binding
    		•  0.501988579312874 bayes_pls_golite062009
  • RNA binding
    		•  0.456300482835377 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.356820770014331 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.333159018967324 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.181009652174389 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.167052456820444 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.165326524526999 bayes_pls_golite062009
  • DNA binding
    		•  0.137717908856835 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.11422473545607 bayes_pls_golite062009
  • protein binding
    		•  0.0943440397971104 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle