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Protein Overview: MRP8

General Information:
Name(s) found: MRP8 / YKL142W [SGD]
Description(s) found:
Found 36 descriptions.
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  • Protein of unknown function; undergoes sumoylation; transcription induced under cell wall stress; protein levels are reduced under anaerobic conditions; originally thought to be a mitochondrial ribosomal protein based on sequence analysis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 219 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial ribosome [ISSLink to PubMed article]
    Biological Process: translation [ISSLink to PubMed article]
    Molecular Function: structural constituent of ribosome [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNEIELLQK QVSELQDLVK KQSLIISKTG ERVLELQLDK QKHDVTDFDS KFSKSISKKS  60
   61 GSATQFDATD FATNEDLVEL VKELQGELNF IEERSIRRLV NSLKKDDDDV IAPLPNADGD 120
  121 IPAISDGVFP KSLKEFKDIP DLKLVRLAKF YERLPPTLKE QEDFENFLEG KVEAFHINET 180
  181 TDEEISKELE KFSKDELDDA FNDVARYLGL SLRRGTEIW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) KEM1 LSP1 MRP8 PIL1
    View Details (MIPS) Mewes HW, et al. (2004) IMG1 MRP8 NAM9 VAR1
    View Details Krogan NJ, et al. (2006) ELM1 GIS4 MRP8 YEL043W YFL054C
    View Details Gavin AC, et al. (2006) BUD2 CCP1 MRP8 PIL1 YLR287C
    View Details Qiu et al. (2008) MRP8 RSM22 VAR1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MRP8 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle