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Protein Overview: ELM1

General Information:
Name(s) found: ELM1 / YKL048C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 640 amino acids

    Gene Ontology:
    Cellular Component: cellular bud neck contractile ring [IDALink to PubMed article]
    Biological Process: axial cellular bud site selection [IMPLink to PubMed article]
    cell morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    response to drug [IMPLink to PubMed articleLink to PubMed article]
    response to osmotic stress [IMPLink to PubMed article]
    pseudohyphal growth [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    glucose metabolic process [IGILink to PubMed article][IMPLink to PubMed article]
    protein amino acid phosphorylation [TASLink to PubMed article]
    budding cell bud growth [IMPLink to PubMed article]
    septin checkpoint [TASLink to PubMed article]
    Molecular Function: protein serine/threonine kinase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPRQLIPTL IPEWAPLSQQ SCIREDELDS PPITPTSQTS SFGSSFSQQK PTYSTIIGEN  60
   61 IHTILDEIRP YVKKITVSDQ DKKTINQYTL GVSAGSGQFG YVRKAYSSTL GKVVAVKIIP 120
  121 KKPWNAQQYS VNQVMRQIQL WKSKGKITTN MSGNEAMRLM NIEKCRWEIF AASRLRNNVH 180
  181 IVRLIECLDS PFSESIWIVT NWCSLGELQW KRDDDEDILP QWKKIVISNC SVSTFAKKIL 240
  241 EDMTKGLEYL HSQGCIHRDI KPSNILLDEE EKVAKLSDFG SCIFTPQSLP FSDANFEDCF 300
  301 QRELNKIVGT PAFIAPELCH LGNSKRDFVT DGFKLDIWSL GVTLYCLLYN ELPFFGENEF 360
  361 ETYHKIIEVS LSSKINGNTL NDLVIKRLLE KDVTLRISIQ DLVKVLSRDQ PIDSRNHSQI 420
  421 SSSSVNPVRN EGPVRRFFGR LLTKKGKKKT SGKGKDKVLV SATSKVTPSI HIDEEPDKEC 480
  481 FSTTVLRSSP DSSDYCSSLG EEAIQVTDFL DTFCRSNESL PNLTVNNDKQ NSDMKTDRSE 540
  541 SSSHSSLKIP TPIKAMIRLK SSPKENGNRT HINCSQDKPS SPLMDRTVGK RTVNNSGARK 600
  601 LAHSSNILNF KAYINSEDSD IRETVEDVKT YLNFADNGQI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ELM1 GIS4 MRP8 YEL043W YFL054C
    View Details Ho Y, et al. (2002) ELM1 TFP1
    View Details Qiu et al. (2008) BNI5 BNR1 BUD4 CDC12 CDC5 ELM1 GIN4 HOF1 HSL1 IQG1 KCC4 SWE1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ELM1 RSM7 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ELM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212]
    [431..443]    		 PSI-BLAST 213.927757 Calmodulin-dependent protein kinase
    2 View Details [213..430] PSI-BLAST 213.927757 Calmodulin-dependent protein kinase
    3 View Details [444..514] PSI-BLAST 15.30103 Calmodulin
    4 View Details [515..640] PSI-BLAST 15.30103 Calmodulin


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle