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Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of AMP. Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein. Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, requiring the presence of DNA. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein. Catalysis of the phosphorylation of a G-protein coupled receptor, thereby modulating its activity. null Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). Catalysis of the reaction: ATP + (myosin-light-chain) = ADP + (myosin-light-chain) phosphate. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin. Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein. Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats. Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a cyclic nucleotide. Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP. Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a 3-phosphoinositide. null null Catalysis of the phosphorylation of ribosomal protein S6. Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol. Catalysis of the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (EIF2). Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: protein serine/threonine kinase activity
Acc: GO:0004674
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.
Synonyms:
  • glycogen synthase kinase activity
  • p82 kinase activity
  • ribosomal S6 protein kinase activity
  • calcium/phospholipid-dependent protein kinase activity
  • protein kinase A activity
  • betaIIPKC
  • protein serine kinase activity
  • protein phosphokinase activity
  • Prp4 protein kinase activity
  • M phase-specific cdc2 kinase activity
  • Wee-kinase activity
  • twitchin kinase activity
  • PKA
  • PKC
  • ATP-protein transphosphorylase activity
  • MAPK
  • AP50 kinase activity
  • ATP:protein phosphotransferase (non-specific) activity
  • GO:0004700
  • serine(threonine) protein kinase activity
  • mitogen-activated protein kinase activity
  • cytidine 3',5'-cyclic monophosphate-responsive protein kinase activity
  • ribosomal protein S6 kinase II activity
  • serine protein kinase activity
  • protein kinase p58 activity
  • T-antigen kinase activity
  • serine/threonine protein kinase activity
  • threonine-specific protein kinase activity
  • phosphorylase B kinase kinase activity
  • protein-serine kinase activity
  • protein glutamyl kinase activity
  • STK32
  • non-specific serine/threonine protein kinase activity
  • dsk1
  • atypical PKC activity
  • Raf kinase activity
  • protein kinase (phosphorylating) activity
  • hydroxyalkyl-protein kinase activity
  • serine kinase activity
  • WEE1Hu
  • protein-cysteine kinase activity
  • atypical protein kinase C activity
  • Raf-1
  • serine-specific protein kinase activity
  • epsilon PKC
  • glycogen synthase a kinase activity
  • Hpr kinase activity
  • HIPK2
  • mitogen-activated S6 kinase activity
  • protein-aspartyl kinase activity
  • casein kinase (phosphorylating) activity
  • Wee 1-like kinase activity
  • protein serine-threonine kinase activity
  • A-kinase activity
Proteins in PDR annotated with:
   This term: 2858 [Search]
   Term or descendants: 3187 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004674 - protein serine/threonine kinase activity (interactive image map)

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Created and Maintained by: Michael Riffle