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Protein Overview: CCP1

General Information:
Name(s) found: CCP1 / YKR066C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 361 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article][TASLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: response to oxidative stress [IMPLink to PubMed article]
    Molecular Function: cytochrome-c peroxidase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG GSNHGWNNWG  60
   61 KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED DEYDNYIGYG PVLVRLAWHT 120
  121 SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV 180
  181 TAVQEMQGPK IPWRCGRVDT PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG 240
  241 AHALGKTHLK NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP 300
  301 TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP FIFKTLEEQG 360
  361 L

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) BUD2 CCP1 MRP8
    View Details Qiu et al. (2008) CCP1 MCR1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CCP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211]
    [330..361]    		 PSI-BLAST 1812.69897 Cytochrome c peroxidase, CCP
    2 View Details [212..329] PSI-BLAST 1812.69897 Cytochrome c peroxidase, CCP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peroxidase activity
    		•  4.90562236110392 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  4.90562236110392 bayes_pls_golite062009
  • antioxidant activity
    		•  4.72975331779519 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.43598009905644 bayes_pls_golite062009
  • catalase activity
    		•  1.75972879470996 bayes_pls_golite062009
  • binding
    		•  0.661610825383382 bayes_pls_golite062009
  • catalytic activity
    		•  0.190481430370391 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle