YRC Public Data Repository - Protein Structure Prediction

Protein:	MRPL1
Organism:	Saccharomyces cerevisiae
Length:	285 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL1.

Description	E-value	Query Range	Subject Range
gi\|190404923 - gi\|190404923\|gb\|EDV08190.1\| 60S ribosomal protein L1, mitochondrial precursor [Saccharomyces cerevis... RM01_YEAST - 54S ribosomal protein L1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=... MRPL1 - Mitochondrial ribosomal protein of the large subunit	5.0E-68	[1..285]	[1..285]
gi\|9957210 - gi\|9957210\|gb\|AAG09267.1\| L1 [EDTA-degrading bacterium BNC1]	2.0E-64	[54..285]	[1..227]
RL1_STAAS - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain MSSA476) GN=rplA PE=3 SV=1 RL1_STAAB - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=rplA PE=3 SV=1 RL1_STAAE - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain Newman) GN=rplA PE=3 SV=1 RL1_STAA2 - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain JH1) GN=rplA PE=3 SV=1 RL1_STAAT - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=rplA PE=3 SV=1 RL1_STAA9 - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain JH9) GN=rplA PE=3 SV=1 gi\|269202161\|ref... - 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus ED98] RL1_STAA8 - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain NCTC 8325) GN=rplA PE=3 SV=1 RL1_STAA3 - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain USA300) GN=rplA PE=3 SV=1 RL1_STAA1 - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=rplA PE=3 SV=1 gi\|227852234, gi... - gi\|227899471\|ref\|ZP_04017276.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus TCH60]... gi\|251802989, gi... - gi\|251813487\|ref\|ZP_04827960.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus TCH70]... gi\|253315648 - gi\|253315648\|ref\|ZP_04838861.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus str. C... gi\|87128269\|gb\|A... - ribosomal protein L1 [Staphylococcus aureus subsp. aureus USA300], ribosomal protein L1 [Staphylococ... gi\|253731143, gi... - gi\|253731143\|ref\|ZP_04865308.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus USA300... gi\|221139611 - gi\|221139611\|ref\|ZP_03564410.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus str. J... gi\|253732546, gi... - gi\|253732546\|ref\|ZP_04866711.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus TCH130... gi\|221141025 - gi\|221141025\|ref\|ZP_03565518.1\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus str. J... gi\|255005332 - gi\|255005332\|ref\|ZP_05143933.2\| 50S ribosomal protein L1 [Staphylococcus aureus subsp. aureus Mu50-o... RL1_STAAW - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain MW2) GN=rplA PE=3 SV=1 RL1_STAAM - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=rplA PE=3 SV=1 RL1_STAAC - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain COL) GN=rplA PE=3 SV=1	4.0E-64	[54..285]	[1..227]
RL1_DEIRA - 50S ribosomal protein L1 OS=Deinococcus radiodurans GN=rplA PE=1 SV=1 RL1_DEIRA - 50S ribosomal protein L1 OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG...	5.0E-64	[54..282]	[1..225]
RL1_THET2 - 50S ribosomal protein L1 OS=Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) GN=rplA PE=... RL1_THETH - 50S ribosomal protein L1 OS=Thermus thermophilus GN=rplA PE=1 SV=3 gi\|2120598 - pir\|\|S66577 ribosomal protein L1 - Thermus aquaticus (fragment)	7.0E-64	[54..284]	[1..227]
RL1_STAAN - 50S ribosomal protein L1 OS=Staphylococcus aureus (strain N315) GN=rplA PE=1 SV=1 gi\|25294922 - pir\|\|D89821 50S ribosomal protein L1 [imported] - Staphylococcus aureus (strain N315)	1.0E-63	[54..285]	[1..227]
RL1_RHIME - 50S ribosomal protein L1 OS=Rhizobium meliloti GN=rplA PE=3 SV=1 RL1_RHIME - 50S ribosomal protein L1 OS=Rhizobium meliloti (strain 1021) GN=rplA PE=3 SV=1	2.0E-63	[54..285]	[1..227]
gi\|28373723\|pdb\|... - Chain d, Structure Of The E. Coli Ribosomal Termination Complex With Release Factor 2 gi\|66361020\|pdb\|... - Chain D, Crystal Structure Of 70s Ribosome With Thrs Operator And Trnas. Large Subunit. The Coordina... gi\|14278034 - gi\|14278034\|pdb\|1GIY\|D Chain D, Crystal Structure Of The Ribosome At 5.5 A Resolution. This File, 1g... gi\|28373723 - gi\|28373723\|pdb\|1ML5\|DD Chain d, Structure Of The E. Coli Ribosomal Termination Complex With Release... gi\|14278034, gi\|... - gi\|66361020\|pdb\|1YL3\|D Chain D, Crystal Structure Of 70s Ribosome With Thrs Operator And Trnas. Larg...	5.0E-63	[56..284]	[2..226]

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Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSVVAIPKI CVTGPARRCF FHTAKKLYAD DYKPAAMSSN APSLTKDQAK KRELKRLVQR  60
   61 KAEAKRPATA SPLYMPVTKA LRYLRAAEVG RPQSQQTINL TTLVVGERGT APLSGSVTFP 120
  121 KPLRYI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [211-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQESLGSMPF RQRGNSISIG VGKCYFTDRE ILQNIISARA AFKTAVDNQK SKKPNILSKT  60
   61 TLSSTHGPGI VIDFA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	207.70927
Match:	1eg0N_
Description:	70S ribosome functional complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	9.98821526471491	bayes_pls_golite062009
structural molecule activity	9.4110731269774	bayes_pls_golite062009
binding	1.22345164833203	bayes_pls_golite062009
protein binding	0.542538198836039	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [127-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIAAFTNDES KLEELREKYP NHLIGGADLV AKIKSGEISV DFDKAFATPD IVPALQSQVA  60
   61 RILGPRGVLP SVKKGTVSDD ISSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	207.70927
Match:	1eg0N_
Description:	70S ribosome functional complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: