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Protein Overview: ESL2

General Information:
Name(s) found: ESL2 / YKR096W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1195 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPETSVQNPL RLSENENTRS MFLSASQQQR PSATPSFPRL VRNTTANLSL SDFQVLNPSS  60
   61 KRQNSNSVYD DINSSKRRIS RPRFSDIEGK NNDHTYPERT TVKESEKNPS PRYVSSSKRA 120
  121 LKRENSVGIT QSSALISKSF SENGGSIAHE KWSPENMIKP LNVSQNSLAF VDAGSDEQSK 180
  181 SEIVGGFQRK SNNSQEINDK DNSARDQDFN NSGNNNNNNN HSSNNNDNNN NNNDDNNNNN 240
  241 NSNSRDNNNN SDDSNEREEN DSCKPASNKR SGIALIQKLQ ELYKVIVKQE IELQERCSQL 300
  301 TNSQTTELKS LWTIYKINTD LVNNYVTFIT TALLPSQPPH DLVIGQEIVE IYRIERRLWV 360
  361 YGTITFLDVL KNFSNFMDPE VCCQFITHVF VSLSTMISDI PSKYSITWLQ RLGDLSRMAI 420
  421 ALYPSSFIDW KLSAEHWYTE AMKYIYNHGK LYYHMSTVQQ NTLEAFVNLG KSVFCQETFT 480
  481 PSPQYMQLVI DNIYQRAFVE RNNGNLRNSL LIEYLKHSEA MLLPSFLESP DLQNVVLSYF 540
  541 IEKFGIDANG CNIFNAEDMF VQNPDFFKYF FRHGPSFAQS HILQIVGFGE PKNPFAILFE 600
  601 LPKYLKERKD KKERKKSSNN DSSVTESSTG NSRNDNEDDD EIMSSTTSIS DHDLLAEFFN 660
  661 DIDTLRRPIL PSMLTNEAWL ETLKFLNMTS LKCGIIVLRK FLHGPLGIAL PHILPWIYFI 720
  721 ISICLKSSQL SDPVSKEFWM IIVKRAFPWD TMVTFMNVLI VYLLDNQTSN SIIGDLCDDY 780
  781 DKLSLSELLE LFNEGEELPE ILGCWGTLWF DTICEKNTHS ISSEDNFQEI GIKDYMALDS 840
  841 PTDGIIFDEK DENGEKFWKR ACRTIFLFRE LSRSFPIGVI IRNDPLIYRS SFQNTNILGS 900
  901 LVFKLEPLCN IHNNIPVLGA LESIIDISEA RSENNTDLHA VPELSVNEGD NIFHYVGYKK 960
  961 LRADYTCFDK NGEFLSASLY TTWYVPNSNN TNIEDNINYN SEKENEGLFL ECIKSDYPEI1020
 1021 DFKTTYFVFD ATSWLRHSAR IFKLAQNRLL RFAICLTTFQ ELRFLRKSKD ENVMEAATRG1080
 1081 IITIRQLYYE NKVLPLRFTG NVATHIEENL EFEEQITWRT HVDEFVIESV MKAQEKLESA1140
 1141 SEPRLSPRRF NYVVLISDDD AMKKKAEEKE IKTLSTRFVF SLCTKLGEQR HLCTD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) CKA1 CKA2 CKB1 CKB2 DIP2 ESL2 KRE33 LCP5 NAN1 NOP1 NOP56 PNO1 PRP40 PTC5 PWP2 RRP5 SNF4 TFP1 TOS3 UTP10 UTP11 UTP13 UTP14 UTP18 UTP21 UTP22 UTP30 UTP6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #14 Mitotic Prep2-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MCA1 ESL2 2 Unpublished Fields Lab Data
    View Screen NAS2 ESL2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ESL2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1019] deduced N/A No confident structure predictions are available.
    2 View Details [1020..1195] MSA 1.003956 View MSA. No confident structure predictions are available.
    3 View Details [271..891] FFAS03 2.16 Crystal structure of the N-terminal domain of human SMG7
    4 View Details [892..988] deduced N/A No confident structure predictions are available.
    5 View Details [989..1195] FFAS03 3.58 No description for 2dokA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.26999948840808 bayes_pls_golite062009
  • protein binding
    		•  0.305336743191506 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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