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Protein Overview: RAD53

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run ASF1 sample 3121 run on DecaLCQ: searched for phosphorylation Green EM, et al (2005)
View Run ASF1 3906: TAP-tagged Green EM, et al (2005)
View Run ASF1 3908: TAP-tagged, includes hir2(delta) in background Green EM, et al (2005)
View Run ASF1 3912: TAP-tagged, strain background includes hpc2(delta) Green EM, et al (2005)
View Run ASF1 sample 3829 Green EM, et al (2005)
View Run ASF1 3829 - low filter Green EM, et al (2005)
View Run ASF1 sample 3928 - Asf1-S-TEV-ZZ (in hir3delta mutant) Green EM, et al (2005)
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

Yeast Two-Hybrid Data

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data RAD53 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..165] PSI-BLAST 904.325697 Phosphotyrosine binding domain of Rad53
2 View Details [166..278]
[491..534]
PSI-BLAST 622.457575 Calmodulin-dependent protein kinase
3 View Details [279..490] PSI-BLAST 622.457575 Calmodulin-dependent protein kinase
4 View Details [535..753] PSI-BLAST 1080.0 Phosphotyrosine binding domain of Rad53
5 View Details [754..821] deduced N/A No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • binding
  • 3.6561903894619 bayes_pls_golite062009
  • transcription regulator activity
  • 3.23926962992034 bayes_pls_golite062009
  • DNA binding
  • 3.12131448113144 bayes_pls_golite062009
  • nucleic acid binding
  • 2.91028042727128 bayes_pls_golite062009
  • transforming growth factor beta receptor, cytoplasmic mediator activity
  • 2.82706319058551 bayes_pls_golite062009
  • histone binding
  • 2.79033314021304 bayes_pls_golite062009
  • protein binding
  • 2.39508335485646 bayes_pls_golite062009
  • receptor signaling protein activity
  • 2.25132862320271 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase signaling protein activity
  • 2.10556565012417 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.95921851331594 bayes_pls_golite062009
  • transcription factor activity
  • 1.89464382469326 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 1.88096476099716 bayes_pls_golite062009
  • double-stranded DNA binding
  • 1.84746485315093 bayes_pls_golite062009
  • kinase activity
  • 1.82476774968305 bayes_pls_golite062009
  • sequence-specific DNA binding
  • 1.78280248668052 bayes_pls_golite062009
  • DNA replication origin binding
  • 1.78246425241581 bayes_pls_golite062009
  • protein kinase activity
  • 1.73373132141588 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 1.66058356077795 bayes_pls_golite062009
  • SMAD binding
  • 1.6101563888469 bayes_pls_golite062009
  • transcription repressor activity
  • 1.60737837207077 bayes_pls_golite062009
  • transcription activator activity
  • 1.53960544319629 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
  • 1.48483625404671 bayes_pls_golite062009
  • transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
  • 1.44498281734982 bayes_pls_golite062009
  • type I transforming growth factor beta receptor binding
  • 1.3333129315031 bayes_pls_golite062009
  • transferase activity
  • 1.29860325699399 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 1.1868962075754 bayes_pls_golite062009
  • promoter binding
  • 1.15188009117562 bayes_pls_golite062009
  • transcription factor binding
  • 0.93544177518754 bayes_pls_golite062009
  • small conjugating protein ligase activity
  • 0.9108432673413 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
  • 0.90981150861416 bayes_pls_golite062009
  • molecular transducer activity
  • 0.767071864136971 bayes_pls_golite062009
  • signal transducer activity
  • 0.767071864136971 bayes_pls_golite062009
  • R-SMAD binding
  • 0.70816286022176 bayes_pls_golite062009
  • chromatin binding
  • 0.62935034847038 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
  • 0.447699674047884 bayes_pls_golite062009
  • co-SMAD binding
  • 0.325865547214071 bayes_pls_golite062009
  • damaged DNA binding
  • 0.279328480488455 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
  • 0.270284689687439 bayes_pls_golite062009
  • specific transcriptional repressor activity
  • 0.0595316953833198 bayes_pls_golite062009
  • protein dimerization activity
  • 0.0504553861724597 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
  • 3.6561903894619 bayes_pls_golite062009
  • transcription regulator activity
  • 3.23926962992034 bayes_pls_golite062009
  • DNA binding
  • 3.12131448113144 bayes_pls_golite062009
  • nucleic acid binding
  • 2.91028042727128 bayes_pls_golite062009
  • transforming growth factor beta receptor, cytoplasmic mediator activity
  • 2.82706319058551 bayes_pls_golite062009
  • histone binding
  • 2.79033314021304 bayes_pls_golite062009
  • protein binding
  • 2.39508335485646 bayes_pls_golite062009
  • receptor signaling protein activity
  • 2.25132862320271 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase signaling protein activity
  • 2.10556565012417 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.95921851331594 bayes_pls_golite062009
  • transcription factor activity
  • 1.89464382469326 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 1.88096476099716 bayes_pls_golite062009
  • double-stranded DNA binding
  • 1.84746485315093 bayes_pls_golite062009
  • kinase activity
  • 1.82476774968305 bayes_pls_golite062009
  • sequence-specific DNA binding
  • 1.78280248668052 bayes_pls_golite062009
  • DNA replication origin binding
  • 1.78246425241581 bayes_pls_golite062009
  • protein kinase activity
  • 1.73373132141588 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 1.66058356077795 bayes_pls_golite062009
  • SMAD binding
  • 1.6101563888469 bayes_pls_golite062009
  • transcription repressor activity
  • 1.60737837207077 bayes_pls_golite062009
  • transcription activator activity
  • 1.53960544319629 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
  • 1.48483625404671 bayes_pls_golite062009
  • transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
  • 1.44498281734982 bayes_pls_golite062009
  • type I transforming growth factor beta receptor binding
  • 1.3333129315031 bayes_pls_golite062009
  • transferase activity
  • 1.29860325699399 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 1.1868962075754 bayes_pls_golite062009
  • promoter binding
  • 1.15188009117562 bayes_pls_golite062009
  • transcription factor binding
  • 0.93544177518754 bayes_pls_golite062009
  • small conjugating protein ligase activity
  • 0.9108432673413 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
  • 0.90981150861416 bayes_pls_golite062009
  • molecular transducer activity
  • 0.767071864136971 bayes_pls_golite062009
  • signal transducer activity
  • 0.767071864136971 bayes_pls_golite062009
  • R-SMAD binding
  • 0.70816286022176 bayes_pls_golite062009
  • chromatin binding
  • 0.62935034847038 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
  • 0.447699674047884 bayes_pls_golite062009
  • co-SMAD binding
  • 0.325865547214071 bayes_pls_golite062009
  • damaged DNA binding
  • 0.279328480488455 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
  • 0.270284689687439 bayes_pls_golite062009
  • specific transcriptional repressor activity
  • 0.0595316953833198 bayes_pls_golite062009
  • protein dimerization activity
  • 0.0504553861724597 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle