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Protein Overview: SDA1

General Information:
Name(s) found: SDA1 / YGR245C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    traversing start control point of mitotic cell cycle [IMPLink to PubMed article]
    ribosome assembly [TASLink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRSRAAML PTNIILLQNL VKRDPESYQE EFLQQYAHYE SLRDIFMLNG LAGGDSAAAT  60
   61 NGLDVGNGSS TMAGTNGTTM STSTSQLIEL VGFVSQVCSC FPRETANFPS ELKQLLLEHH 120
  121 KSLPFELKEK ILSCLTMLRN KDVITAEELI QSLFPLLVAY SSHGNSLGVN SHAKELRKII 180
  181 YTNLISLLKS CNTNGKNQKL NKSTQAVCFN LLDQPDSQGI WATKLTRELW RRGIWDDSRT 240
  241 VEIMTQAALH QDVKIVMSGV MFFLDADRER EENFEENSED EDGFDLDALR HKMQVNKKTG 300
  301 RRGKKLENAI KTVKKKKKNG PGAPQGYLNF SAIHLLRDPQ GFAEKLFKEH LSGKTKNKFD 360
  361 MEQKISLMQL LSRLIGTHKL IVLGIYTFFL KYLTPKQRDV TRIMSACAQA CHDLVPPEVI 420
  421 NVMVRKIADE FVSDGVANEV AAAGINTIRE ICSRAPLAID EILLQDLVEY KGSKAKGVNM 480
  481 AAKSLIALYR DVAPEMLKKK DRGKNAAMEV QEAKKGGKDS KRPQFGADNS VQGIAGIELL 540
  541 AKWKKEHGEE SENEDADANW EVDVDSEEDD VDGEWVTMDS DKEYDVDMED SDDEKDNAKG 600
  601 KESDSDLELS DDDDEKEVKD EQEDADIDPE AAFREIASTR ILTPADFAKL QELRNEESVA 660
  661 KIMGIHKQDK REELVDASTL TGPIKYKQSR EERLQKVLEG REGRDKFGSR RGKRDNMRST 720
  721 TNREKERRKN FVMSIHKRSV RGKQKMSLRD KQKVLRAHIT KQKKKGY

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BUD20 CIC1 DBP10 DRS1 ERB1 HAS1 IPI1 IPI3 MDN1 MRT4 NOG1 NOG2 NOP15 NOP7 NSA2 NUG1 RIX1 RLP7 RPF1 RSA4 SDA1 TIF6 YTM1
    View Details Krogan NJ, et al. (2006) CHA1 SDA1
    View Details Gavin AC, et al. (2006) ARX1 BUD20 FPR4 IPI3 MRT4 NIP7 NOG1 NOG2 NOP2 NSA2 NUG1 RIX1 RPF2 RSA4 SDA1 TIF6
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..196] ab initio 12.94 No description for 1gw5B was found.
    3 View Details [197..325] ab initio 12.94 No description for 1gw5B was found.
    4 View Details [326..501] ab initio 12.94 No description for 1gw5B was found.
    5 View Details [502..682] MSA 14.047997 View MSA. No confident structure predictions are available.
    6 View Details [683..767] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle