General Information: |
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Name(s) found: |
SIN3 /
YOL004W
[SGD]
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Description(s) found:
Found 23 descriptions. SHOW ALL |
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Organism: | Saccharomyces cerevisiae |
Length: | 1536 amino acids |
Gene Ontology: |
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Cellular Component: |
Sin3 complex
[IPI]
histone deacetylase complex [IPI] |
Biological Process: |
negative regulation of transcription from RNA polymerase II promoter
[IMP]
chromatin silencing at rDNA [IMP] telomere maintenance [IMP] double-strand break repair via nonhomologous end joining [IMP] histone deacetylation [IMP] chromatin silencing at silent mating-type cassette [IMP] positive regulation of transcription from RNA polymerase II promoter [IMP] chromatin silencing at telomere [IMP] |
Molecular Function: |
transcription coactivator activity
[IMP]
histone deacetylase activity [IMP] transcription corepressor activity [IMP] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSQVWHNSNS QSNDVATSND ATGSNERNEK EPSLQGNKPG FVQQQQRITL PSLSALSTKE 60 61 EDRRDSNGQQ ALTSHAAHIL GYPPPHSNAM PSIATDSALK QPHEYHPRPK SSSSSPSINA 120 121 SLMNAGPAPL PTVGAASFSL SRFDNPLPIK APVHTEEPKS YNGLQEEEKA TQRPQDCKEV 180 181 PAGVQPADAP DPSSNHADAN DDNNNNENSH DEDADYRPLN VKDALSYLEQ VKFQFSSRPD 240 241 IYNLFLDIMK DFKSQAIDTP GVIERVSTLF RGYPILIQGF NTFLPQGYRI ECSSNPDDPI 300 301 RVTTPMGTTT VNNNISPSGR GTTDAQELGS FPESDGNGVQ QPSNVPMVPS SVYQSEQNQD 360 361 QQQSLPLLAT SSGLPSIQQP EMPAHRQIPQ SQSLVPQEDA KKNVDVEFSQ AISYVNKIKT 420 421 RFADQPDIYK HFLEILQTYQ REQKPINEVY AQVTHLFQNA PDLLEDFKKF LPDSSASANQ 480 481 QVQHAQQHAQ QQHEAQMHAQ AQAQAQAQAQ VEQQKQQQQF LYPASGYYGH PSNRGIPQQN 540 541 LPPIGSFSPP TNGSTVHEAY QDQQHMQPPH FMPLPSIVQH GPNMVHQGIA NENPPLSDLR 600 601 TSLTEQYAPS SIQHQQQHPQ SISPIANTQY GDIPVRPEID LDPSIVPVVP EPTEPIENNI 660 661 SLNEEVTFFE KAKRYIGNKH LYTEFLKILN LYSQDILDLD DLVEKVDFYL GSNKELFTWF 720 721 KNFVGYQEKT KCIENIVHEK HRLDLDLCEA FGPSYKRLPK SDTFMPCSGR DDMCWEVLND 780 781 EWVGHPVWAS EDSGFIAHRK NQYEETLFKI EEERHEYDFY IESNLRTIQC LETIVNKIEN 840 841 MTENEKANFK LPPGLGHTSM TIYKKVIRKV YDKERGFEII DALHEHPAVT APVVLKRLKQ 900 901 KDEEWRRAQR EWNKVWRELE QKVFFKSLDH LGLTFKQADK KLLTTKQLIS EISSIKVDQT 960 961 NKKIHWLTPK PKSQLDFDFP DKNIFYDILC LADTFITHTT AYSNPDKERL KDLLKYFISL1020 1021 FFSISFEKIE ESLYSHKQNV SESSGSDDGS SIASRKRPYQ QEMSLLDILH RSRYQKLKRS1080 1081 NDEDGKVPQL SEPPEEEPNT IEEEELIDEE AKNPWLTGNL VEEANSQGII QNRSIFNLFA1140 1141 NTNIYIFFRH WTTIYERLLE IKQMNERVTK EINTRSTVTF AKDLDLLSSQ LSEMGLDFVG1200 1201 EDAYKQVLRL SRRLINGDLE HQWFEESLRQ AYNNKAFKLY TIDKVTQSLV KHAHTLMTDA1260 1261 KTAEIMALFV KDRNASTTSA KDQIIYRLQV RSHMSNTENM FRIEFDKRTL HVSIQYIALD1320 1321 DLTLKEPKAD EDKWKYYVTS YALPHPTEGI PHEKLKIPFL ERLIEFGQDI DGTEVDEEFS1380 1381 PEGISVSTLK IKIQPITYQL HIENGSYDVF TRKATNKYPT IANDNTQKGM VSQKKELISK1440 1441 FLDCAVGLRN NLDEAQKLSM QKKWENLKDS IAKTSAGNQG IESETEKGKI TKQEQSDNLD1500 1501 SSTASVLPAS ITTVPQDDNI ETTGNTESSD KGAKIQ |
The following runs contain data for this protein:
  | BAIT | COMMENTS | PUBLICATION |
View Run | sample cbf3 from feb 2005 | Sandall S, et all (2006) | |
View Run | No Comments | Schneider, DA, et al. (2006) | |
View Run | Sample 2- cpn2 from june 2005 | McCusker D, et al (2007) | |
View Run | Sample 3 - cpn + atp, from june 2005 | McCusker D, et al (2007) | |
View Run | Sample boi 1 with ha tag from october 2005 | McCusker D, et al (2007) | |
View Run | Sample boi1 with gst from october 2005 | McCusker D, et al (2007) | |
View Run | #29 Asynchronous Prep5-TiO2 Flowthrough | Keck JM, et al. (2011) |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
New Feature: Upload Your Own Microscopy Data
  | PROTEIN(S) | PUBLICATION |
View Data |
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Huh WK, et al. (2003) |
Domains predicted:
# | Region(s) | Method | Confidence | Match Description | |
1 | View Details | [1..237] | 11.5 | RBP1 | |
2 | View Details | [238..321] | 19.346787 | Paired amphipathic helix repeat No confident structure predictions are available. | |
3 | View Details | [322..423] | N/A | No confident structure predictions are available. | |
4 | View Details | [424..489] | 19.69897 | Paired amphipathic helix repeat No confident structure predictions are available. | |
5 | View Details | [490..606] | 172.134302 | Sin3A | |
6 | View Details | [607..732] | 11.33 | Sin3A | |
7 | View Details | [733..1024] | 1.021966 | View MSA. No confident structure predictions are available. | |
8 | View Details | [1025..1368] | 2.019929 | View MSA. No confident structure predictions are available. | |
9 | View Details | [1369..1536] | 2.014993 | View MSA. No confident structure predictions are available. | |
10 | View Details | [1179..1355] | N/A | No confident structure predictions are available. | |
11 | View Details | [1356..1449] | N/A | No confident structure predictions are available. | |
12 | View Details | [1450..1536] | N/A | No confident structure predictions are available. |
Functions predicted (by domain):
# | Gene Ontology predictions | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 |
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3 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5 |
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6 |
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7 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12 | No functions predicted. |
Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.95 |
Source: Reynolds et al. (2008)