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Protein Overview: TOP1

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data TOP1 Huh WK, et al. (2003)
View Data TOP1 and NOP56 Huh WK, et al. (2003)

Protein Structure Data


[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..123] MSA 7.064997 View MSA. No confident structure predictions are available.
2 View Details [124..158]
[253..290]
[307..366]
PSI-BLAST 1352.0 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
3 View Details [159..252]
[291..306]
PSI-BLAST 1352.0 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
4 View Details [367..480] PSI-BLAST 57.9794 Eukaryotic DNA topoisomerase I, catalytic core
5 View Details [481..534] PSI-BLAST 3.221849 Tropomyosin
6 View Details [535..615] PSI-BLAST 3.221849 Tropomyosin
7 View Details [616..719] PSI-BLAST 3.221849 Tropomyosin
8 View Details [720..769] ORFEUS 12.79 Eukaryotic DNA topoisomerase I, dispensable insert domain; Eukaryotic DNA topoisomerase I, catalytic core; Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2
Term Confidence Notes
  • catalytic activity
  • 0.078956976886834 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle