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Protein Overview: REV1

General Information:
Name(s) found: REV1 / YOR346W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 985 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: mutagenesis [IMPLink to PubMed article]
    DNA repair [IMPLink to PubMed article]
    DNA-dependent DNA replication [IDALink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [IDALink to PubMed article]
    deoxycytidyl transferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEHGGLVDL LDSDLEYSIN RETPDKNNCL SQQSVNDSHL TAKTGGLNAR SFLSTLSDDS  60
   61 LIEYVNQLSQ TNKNNSNPTA GTLRFTTKNI SCDELHADLG GGEDSPIARS VIEIQESDSN 120
  121 GDDVKKNTVY TREAYFHEKA HGQTLQDQIL KDQYKDQISS QSSKIFKNCV IYINGYTKPG 180
  181 RLQLHEMIVL HGGKFLHYLS SKKTVTHIVA SNLPLKKRIE FANYKVVSPD WIVDSVKEAR 240
  241 LLPWQNYSLT SKLDEQQKKL DNCKTVNSIP LPSETSLHKG SKCVGSALLP VEQQSPVNLN 300
  301 NLEAKRIVAC DDPDFLTSYF AHSRLHHLSA WKANLKDKFL NENIHKYTKI TDKDTYIIFH 360
  361 IDFDCFFATV AYLCRSSSFS ACDFKRDPIV VCHGTKNSDI ASCNYVARSY GIKNGMWVSQ 420
  421 AEKMLPNGIK LISLPYTFEQ FQLKSEAFYS TLKRLNIFNL ILPISIDEAV CVRIIPDNIH 480
  481 NTNTLNARLC EEIRQEIFQG TNGCTVSIGC SDSLVLARLA LKMAKPNGYN ITFKSNLSEE 540
  541 FWSSFKLDDL PGVGHSTLSR LESTFDSPHS LNDLRKRYTL DALKASVGSK LGMKIHLALQ 600
  601 GQDDEESLKI LYDPKEVLQR KSLSIDINWG IRFKNITQVD LFIERGCQYL LEKLNEINKT 660
  661 TSQITLKLMR RCKDAPIEPP KYMGMGRCDS FSRSSRLGIP TNEFGIIATE MKSLYRTLGC 720
  721 PPMELRGLAL QFNKLVDVGP DNNQLKLRLP FKTIVTNRAF EALPEDVKND INNEFEKRNY 780
  781 KRKESGLTSN SLSSKKKGFA ISRLEVNDLP STMEEQFMNE LPTQIRAEVR HDLRIQKKIQ 840
  841 QTKLGNLQEK IKRREESLQN EKNHFMGQNS IFQPIKFQNL TRFKKICQLV KQWVAETLGD 900
  901 GGPHEKDVKL FVKYLIKLCD SNRVHLVLHL SNLISRELNL CAFLNQDHSG FQTWERILLN 960
  961 DIIPLLNRNK HTYQTVRKLD MDFEV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CIK1 GDH2 REV1
    View Details Krogan NJ, et al. (2006) AIM26 APC9 BEM3 FMP27 IRA1 MDM36 MID1 NUP42 REV1 SEC20 SML1 TCO89 TOP1 YDR396W YGL024W ZAP1 ZIM17

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data REV1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] deduced N/A No confident structure predictions are available.
    2 View Details [104..251] PSI-BLAST 3.522879 Breast cancer associated protein, BRCA1
    3 View Details [252..342] deduced N/A No confident structure predictions are available.
    4 View Details [343..365]
    [439..537]    		 PSI-BLAST 197.0103 DinB homolog (DBH)
    5 View Details [366..438]
    [538..619]    		 PSI-BLAST 197.0103 DinB homolog (DBH)
    6 View Details [620..807] PSI-BLAST 197.0103 DinB homolog (DBH)
    7 View Details [808..985] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle