YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MID1

General Information:
Name(s) found: MID1 / YNL291C [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 548 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: calcium ion transport [IDALink to PubMed article]
    Molecular Function: stretch-activated, cation-selective, calcium channel activity [IDALink to PubMed article]
    calcium channel activity [IMPLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVWQALFVV YCLFTTSIHG LFQDFNPFAN KNISLKFPSL NRWEKNVMAT GQQTIINSDS  60
   61 IYEWTPILSN ITAGKKDSFV FTIDAEASGY GFAPTYEVLM FISGNICQMP MNRSDVDLTI 120
  121 YYSFNETVLE NPNIGQSAVF QDGYIQALAI SPVQSSSSNA TSTYSNLYVV AELVNSTTEQ 180
  181 PLSSSDASEN WEYRLSISEN DLVFQWDVRP WVEVLDTDMN SALLSTGNVT ADAKVYHNYS 240
  241 IYDPSLYDLY VYSYEDSVQL NQNYNLSLCA VKNGPYLVSS QNTSNATVTS NSTNPLERTD 300
  301 LAIQKKITEY GGSVTEMFYV TGLNASTTYV AYLTKKISNG DGLSSVGGIL FSHVYFTTRS 360
  361 TDVCSLIFGL DFCSDVAYSV PTSSFSVGNK TLMAQTYDHI AEALYANFSK ALQLISCDAD 420
  421 KDARYSPVMT CDDCAEAYRD WVCAVSIPRC TTTSSQYYIH RDKSHNRNDY LNKFIKPLDD 480
  481 YYEILPCIDM CYTLVRNCPS DFQFSCPNDL TTEDLLYQSY NFYMDTDYST CNYIGNSSLM 540
  541 VIHPLDDT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AIM26 APC9 BEM3 FMP27 IRA1 MDM36 MID1 NUP42 REV1 SEC20 SML1 TCO89 TOP1 YDR396W YGL024W ZAP1 ZIM17

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] MSA 1.00389 View MSA. No confident structure predictions are available.
    2 View Details [246..548] deduced N/A No confident structure predictions are available.
    3 View Details [218..341] deduced N/A No confident structure predictions are available.
    4 View Details [342..548] FFAS03 1.62 Secreted Frizzled-related protein 3 (SFRP-3;fzb)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transmembrane receptor activity
    		•  1.81467703148571 bayes_pls_golite062009
  • receptor activity
    		•  1.79586924429875 bayes_pls_golite062009
  • binding
    		•  1.58747760460167 bayes_pls_golite062009
  • protein binding
    		•  1.24658797699128 bayes_pls_golite062009
  • signal transducer activity
    		•  1.02200332848929 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.02200332848929 bayes_pls_golite062009
  • Wnt receptor activity
    		•  0.268954856682316 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle