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Catalysis of the removal of one or more acetyl groups from a histone, requiring NAD. Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. Catalysis of the removal of an acetyl group from lysine at position 9 of the histone H3 protein. Catalysis of the hydrolysis of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes. Catalysis of the removal of one or more acetyl groups from a histone, independently of NAD. Catalysis of the removal of an acetyl group from lysine at position 16 of the histone H3 protein. Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. Catalysis of the removal of an acetyl group from lysine at position 14 of the histone H3 protein.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: histone deacetylase activity
Acc: GO:0004407
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.
Proteins in PDR annotated with:
   This term: 123 [Search]
   Term or descendants: 152 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004407 - histone deacetylase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle