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Protein Overview: STB1

General Information:
Name(s) found: STB1 / YNL309W [SGD]
Description(s) found:
Found 17 descriptions.
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  • Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 420 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Sin3 complex [IPILink to PubMed article]
    Biological Process: G1/S transition of mitotic cell cycle [IEPLink to PubMed article][IGILink to PubMed article]
    Molecular Function: transcription activator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQPQMSPEK EQELASKILH RAELAQMTRQ LKLGLSNVPS TKRKQDSTTK KRSGEDAEDV  60
   61 DEDHKTLLEA ISPAKKPLHD DTNKMTVISP VKFVEKPNTP PSSRQRKAED RSQQIKPRKE 120
  121 DTPSTPRASA TPIILPHASS HYQRPHDKNF MTPKRNNNNS SNHSNNNNNI KKKAAGSKDA 180
  181 PQDSDNTAGA DLLMYLATSP YNKSSHHGTP MAVRMPTTPR SYHYASQLSL NGNTASTSND 240
  241 AVRFSHIKPS ASSPQSTFKS NLLPNFPDES LMDSPSLYLS NNNGSVQATL SPQQRRKPTT 300
  301 NTLHPPSNVP TTPSRELNGT NFNLLRTPNF NMGDYLHNLF SPSPRVPAQQ GASNTSASIP 360
  361 SVPAMVPGSS SNTSAIATAA ISSHTTNNFL DMNANGIPLI VGPGTDRIGE GESIDDKLTD 420
  421

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) RPD3 SIN3 STB1 STB2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC28 STB1 2 Unpublished Fields Lab Data
    View Screen CDC28 STB1 2 Unpublished Fields Lab Data
    View Screen CLB5 STB1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data STB1 and NOP56 Huh WK, et al. (2003)
    View Data STB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] deduced N/A No confident structure predictions are available.
    2 View Details [233..420] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle