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Protein Overview: STB2

General Information:
Name(s) found: STB2 / YMR053C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 850 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IPILink to PubMed article]
    Sin3 complex [IPILink to PubMed article]
    Biological Process: histone deacetylation [IPILink to PubMed article]
    Molecular Function: transcription repressor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMADTIATG DKTSQFDGKH MQDLERIYST RDTLDDNFFG ERGQKDANGD YYDELNNEET  60
   61 NYSGSSYYGH SDDSEVVGLI KNDTVSQLPP LDSFIFPDSR ALFLLDLGNY ADLTYEEIIV 120
  121 HGFEIYIVEQ WVACRNLSTL ITSYTGNSQD TISGVRVVLP KDTSMWPGRF RLYFEELMEF 180
  181 ARPKFTPKGT LFITNLSGVS FGLNLLHVEC GDLRTIWKDF EVNFDLKNLH CGGRSANLLC 240
  241 PPTMASLDKF SQLFKIPTNG FIAQYPQMIQ QQQPRLPEEE YKTVGNSKCR NTDSKSPVVE 300
  301 MVTLIQISLS YFNLLSKNYQ TDGLLCEDTK RAIDEWWETY GKLYLGTEKP RNECTLGPTT 360
  361 VAGLISLILC CYFKLMIENC ISSKDPFDEA GFFQGIYNFQ KKHGLNKRKS RVYLDPRTLE 420
  421 KLFEVTAKVS SKDIFKLKKM VTSTVQDIIG KGNPINLSHK ILTTDLDTLI HNIHGGSVGL 480
  481 LWKGKGHPRK CCTDISNEEF LKFNYQRGDP DGQIREREML LEKFRLERIA YAQKHASKKV 540
  541 SSSSLDTSED IGRTNAMPSS ATVSSMFPNY DNTKYAYNFG INKLYQGEYY RRNSFPYCKD 600
  601 RTHDNIYEDL SELKEKSSRL YRCNSSSAVQ NIVEKWDLPF DPSVVRIARD LLRMKYDIQA 660
  661 QQHIQEMDEH YMGKLNKEGT VGQYSKFNER YKRLQELYKK YSDGAKVFEG RFEDIDNKQQ 720
  721 LLLHEMQELN SLSSRLKYDM RILEVRVRDI ESSVAQFDSK LIGLKSSLQG QGKTGICSAI 780
  781 DPKSDKDEYD RCVNDLMTTN NPTYEALCLK MLSRRYFKDL KNDTVGWFRW LFGNNSLHNN 840
  841 ASEDDRGIRV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) RPD3 SIN3 STB1 STB2
    View Details Qiu et al. (2008) HDA2 HDA3 HOS1 HOS4 RPD3 SDS3 SIF2 SIN3 STB2 SUM1 TFB5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FRT2 STB2 2 Unpublished Fields Lab Data
    View Screen VAM7 STB2 2 Uetz P, et al. (2000)
    View Screen NSE5 STB2 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..600] deduced N/A No confident structure predictions are available.
    2 View Details [601..850] MSA 1.003883 View MSA. No confident structure predictions are available.
    3 View Details [285..850] FFAS03 0.951 No description for 2oevA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle