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Protein Overview: NSA1

General Information:
Name(s) found: NSA1 / YGL111W [SGD]
Description(s) found:
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  • gi|6321327|ref|NP_011404.1| Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; Nsa1p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S64119 hypothetical protein YGL111w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1723904|sp|P53136.1|NSA1_YEAST RecName: Full=Ribosome biogenesis protein NSA1; AltName: Full=NOP7-associated protein 1 [NCBI NR]
  • gi|1322659|emb|CAA96818.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1310713|emb|CAA66241.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Uncharacterized protein YGL111W - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • Ribosome biogenesis protein NSA1 OS=Saccharomyces cerevisiae GN=NSA1 PE=1 SV=1 [Swiss-Prot]
  • NSA1 Constituent of 66S pre-ribosomal particles [mips]
  • Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis [SGD]
  • YGL111W, Chr VII from 299976-301367 [yeast_orfs2]
  • Chr VII from 299976-301367 [yeastorf3.fasta]
  • Chr VII from 299979-301370 [yeastorf4.fasta]
  • (P53136) Hypothetical 51.9 kDa protein in TAF60-MLC1 intergenic region [4932.FASTACCERV.txt]
  • NSA1 SGDID:S0003079, Chr VII from 299979-301370, Verified ORF [yeastflysequest.fasta]
  • NSA1 SGDID:S0003079, Chr VII from 299981-301372, Verified ORF [10112005cervSGD.fasta]
  • Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis [Saccharomyces cerevisiae]gi|1322659|emb|CAA96818.1| unnamed protein product [Saccharomyces cerevisiae]gi|1310713|emb|CAA66241.1| unnamed protein product [Saccharom [nrdb_11152004_Chlamydomonas]
  • NSA1 SGDID:S000003079, Chr VII from 299981-301372, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Uncharacterized protein YGL111W [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; Nsa1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Ribosome biogenesis protein NSA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NSA1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • NSA1 SGDID:S000003079, Chr VII from 299978-301369, Genome Release 64-1-1, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" [yeast-030211-contam.fasta]
  • NSA1 SGDID:S000003079, Chr VII from 299978-301369, Genome Release 64-2-1, Verified ORF, "Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis" [20141208_orf_trans.fasta]
  • YGL111W SGDID:S000003079, Chr VII from 299978-301369, Genome Release 64-1-1, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: ribosomal large subunit biogenesis [IMPLink to PubMed article][IPILink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLVSCVDS GSIKEVLCNI GTDTSVQSAL QPFHVAPHLA EGLKAYVDRM WVISEDEAIL  60
   61 ARNSGVVELV KISKHLKENE ALQVDPKGES KNEKSLSDDL PKFDISEFEI TSSVSDLFDD 120
  121 AKLESLSSKS VKRTKLVDGF VTLCPIKKDS SNNTFVAATK SGLLHIIKKG EDKKLIKLAS 180
  181 LGLKAPVEFL QLYDLEDTDT DKYIFAYGGE ENLIKLVEID SSFQSLKQIW EAKNVKNDRL 240
  241 DMRVPVWPMA LRFLEPSPGK TEKGKLNYQF AAITRWSHLT KYSTQHGRKP FAQIDLLPNR 300
  301 EPLSQMEVFD AKGENVVSSL GNFQSETFNE LNVITTDYKK NVFKFDGNGR MLGKVGRDDI 360
  361 TGSSTYIHVH DGKYLLQGGL DRYVRIFDIK TNKMLVKVYV GSRINFIVML DDVEIEMPLS 420
  421 PSAKAAKGKQ KRKVTELEED ADELWNKLEG KVAASKASKK SKI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BRX1 CIC1 DBP10 DBP9 DRS1 EBP2 ERB1 HAS1 MAK21 MRT4 NIP7 NOC2 NOC3 NOG1 NOP15 NOP2 NOP4 NOP7 NSA1 NSA2 NUG1 PUF6 RIX1 RIX7 RLP7 RPF1 RPL23B, RPL23A RPL25 SPB1 SPB4 TIF6 YTM1
    View Details Krogan NJ, et al. (2006) NSA1 PMS1 RDR1
    View Details Gavin AC, et al. (2006) NSA1 RPF1
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
    View Details Ho Y, et al. (2002) ABP1 ACO1 AIM41 ATP4 BRX1 BUD14 CAR2 CCT6 CDC14 CFT1 CIC1 CKB1 CLU1 COR1 COX6 CRZ1 CYS4 DCP1 DCP2 DNL4 DNM1 EDC3 EDE1 EGD2 ENP1 ERB1 FET4 FIN1 FIP1 FPR3 FPR4 GAR1 GAS1 GCN3 GDE1 GLC7 GLC8 GND1 GPH1 GUS1 HAS1 HER1 HHF1, HHF2 HRR25 HSP104 HTA1 HXT7 HYP2 IPP1 KEL1 KGD1 LOC1 LSP1 LTV1 MAK16 MDH1 MDS3 MET6 MGE1 MHP1 MRT4 MUB1 NIP7 NMD3 NOC2 NOC3 NOG1 NOP1 NOP15 NOP2 NOP56 NOP7 NSA1 NSA2 NUG1 OYE2 PEX19 PHO84 PIL1 PIN4 PRP43 PTC4 PUF3 REG1 RIO2 RPC19 RPF2 RPM2 RRP1 RRP17 RRT6 SAH1 SAP185 SAP190 SAS10 SCD5 SCS2 SDS22 SEC2 SEC23 SEC53 SEN1 SES1 SFB3 SGM1 SIT4 SPB1 SPB4 SSQ1 SUI2 SUI3 TIF6 TMA19 TSR1 UBR2 VMA4 YBR225W YER138C YPL009C YTM1
    View Details Qiu et al. (2008) ENP1 ERB1 FPR4 GAR1 NSA1 NUG1 PXR1 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NSA1 and NOP56 Huh WK, et al. (2003)
    View Data NSA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..463] ORFEUS 11.75 No description for 1scgB was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle