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Protein Overview: MUB1

General Information:
Name(s) found: MUB1 / YMR100W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein that interacts with E2 and E3 enzymes Ubr2p and Rad6p and is required for ubiquitylation and degradation of Rpn4p; contains a MYND domain (residues 512 to 555); has a short half-life; has similarity to Aspergillus nidulans samB gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: regulation of cell budding [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDSNHRSLT SNKPIVTITS TVYDRRALDI NSSIPLINSL NYLTYLTSNS SKVRETVAND  60
   61 GALERLVSIL RSCHLSLFEL LDLDLENFNE HENIKDLWKE KRLALCAWKW TLTFQCLVLT 120
  121 GTRGTEQIRK KVVMSGVLSV LVTVLDNYLL YHKNYDFIKD QTMTFDFKGI TTETMYKFMR 180
  181 KDENETYQQY IEFITGQDKL KLSTDKNFLN ERLVAPSMTI PTDFSDIWGR FADLASNFEP 240
  241 DQERHDDDID IDSEVESENF DAHKNFFSQP DINRPTISTP REFFLGRIVP KQDDVIWSLQ 300
  301 LLAFVSKYTY MKSTLQNVEL VESLSFRSMA YKIKQRISEE NDLEEQERDV TVKLSSLYPY 360
  361 LSKNPENNSK VKALDTSKMD PFFKELEELS NRCQQEEQNE ICNNHCPVLN LFERYRVPKP 420
  421 SDDNAYGKDK ERINLRKKIS DNFERRWSYD KMKKELTNIV YKNKVLTNVV NIFPLVEKYT 480
  481 VSAENTHDVI YWSSVIMRNS CRKNEILGVR QCANFSCGKW EDFPRQFAKC RRCKRTKYCS 540
  541 RKCQLKAWGY HRYWCHEVGS SHMRSTNTTT GVNTPNEPSS LNATATTAAD VSNSTSTFTP 600
  601 NISTTVPDEI SNRDENSIPE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CUE4 MUB1 RAD18 RAD6
    View Details Ho Y, et al. (2002) ACO1 CCT6 CDC14 EGD2 ERB1 GND1 GUS1 HAS1 HXT7 MET6 MRT4 MUB1 NOC2 NOC3 NOG1 NSA1 NUG1 PRP43 SAH1 SCS2 SEC53 SPB4 SSQ1 TIF6 UBR2 YTM1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MCM16 No Comments Cheeseman IM, et al. (2002)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..215] MSA 2.003947 View MSA. Confident ab initio structure predictions are available.
    2 View Details [216..466] deduced N/A No confident structure predictions are available.
    3 View Details [467..620] Pfam 18.79588 MYND finger No confident structure predictions are available.
    4 View Details [516..620] PSI-BLAST 12.30103 No description for 2d8qA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.14656986206324 bayes_pls_golite062009
  • protein binding
    		•  0.269281331533887 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle