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Protein Overview: MCM16

General Information:
Name(s) found: MCM16 / YPR046W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 181 amino acids

    Gene Ontology:
    Cellular Component: condensed nuclear chromosome kinetochore [IDALink to PubMed article]
    Biological Process: chromosome segregation [IPILink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNSSEKQWE RIQQLEKEHV EVYRELLITL DRLYLIRKHN HAVILSHTQQ RLLEIRHQLQ  60
   61 INLEKTALLI RLLEKPDNTN VLFTKLQNLL EESNSLDYEL LQSLGAQSSL HKQLIESRAE 120
  121 RDELMSKLIE LSSKFPKPTI PPDDSDTAGK QVEVEKENET IQELMIALQI HSGYTNISYT 180
  181 I

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) CTF3 MCM16 MCM22
    View Details Krogan NJ, et al. (2006) AME1 ARG5,6 CHL4 CTF19 CTF3 IML3 MCM16 MCM21 MCM22 NKP1 NKP2 OKP1 PRP18 SET4 YNR062C
    View Details Qiu et al. (2008) MCM16 MCM21 MCM22

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CHL4 No Comments Cheeseman IM, et al. (2002)
    View Run MCM16 No Comments Cheeseman IM, et al. (2002)
    View Run NSL1 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MCM16 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] Pcons 1.88 Granulocyte-colony stimulating factor (G-CSF)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle