Protein Overview: NKP2

General Information:
Name(s) found:	NKP2 / YLR315W [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p) [SGD]
Organism:	Saccharomyces cerevisiae
Length:	153 amino acids
Gene Ontology:
Cellular Component:	spindle pole body [IDA] kinetochore [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEQLLHNY VSDSLLTTLI SFQEFKQQLQ SYTSDEQQLQ HWYELLQARD ARVTSELEAR  60
   61 IKQFFITLRS RLLRFLESEQ LSHSLSLETL IDALYKINDL LQQRLQILDD AIQEKTSELA 120
  121 EFENMVRSPS AGDNAIPGLL QIIQSYINLL EEN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		AME1 IML3 MCM21 MCM22 NKP1 NKP2 OKP1
View Details	Krogan NJ, et al. (2006)		AME1 ARG5,6 CHL4 CTF19 CTF3 IML3 MCM16 MCM21 MCM22 NKP1 NKP2 OKP1 PRP18 SET4 YNR062C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CHL4	No Comments	Cheeseman IM, et al. (2002)
View Run	MCM16	No Comments	Cheeseman IM, et al. (2002)
View Run	NSL1	No Comments	Hazbun TR, et al. (2003)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MVP1	NKP2	2	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	NKP2 and SPC42	Huh WK, et al. (2003)
View Data	NKP2	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..153]	ORFEUS	8.32	Apolipoprotein E
2	View Details	[85..153]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2