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Protein Overview: NKP2

General Information:
Name(s) found: NKP2 / YLR315W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p) [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 153 amino acids

    Gene Ontology:
    Cellular Component: spindle pole body [IDALink to PubMed article]
    kinetochore [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEQLLHNY VSDSLLTTLI SFQEFKQQLQ SYTSDEQQLQ HWYELLQARD ARVTSELEAR  60
   61 IKQFFITLRS RLLRFLESEQ LSHSLSLETL IDALYKINDL LQQRLQILDD AIQEKTSELA 120
  121 EFENMVRSPS AGDNAIPGLL QIIQSYINLL EEN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) AME1 IML3 MCM21 MCM22 NKP1 NKP2 OKP1
    View Details Krogan NJ, et al. (2006) AME1 ARG5,6 CHL4 CTF19 CTF3 IML3 MCM16 MCM21 MCM22 NKP1 NKP2 OKP1 PRP18 SET4 YNR062C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CHL4 No Comments Cheeseman IM, et al. (2002)
    View Run MCM16 No Comments Cheeseman IM, et al. (2002)
    View Run NSL1 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MVP1 NKP2 2 Unpublished Fields Lab Data
    View Screen YHR122W NKP2 1 Hazbun TR, et al. (2003)
    View Screen LIA1 NKP2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NKP2 and SPC42 Huh WK, et al. (2003)
    View Data NKP2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] ORFEUS 8.32 Apolipoprotein E
    2 View Details [85..153] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle