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Protein Overview: POL2

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
View Run RPA135 No Comments Schneider, DA, et al. (2006)
View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

  BAIT PREY HITS PUBLICATION
View Screen PRP42 POL2 1 Unpublished Fields Lab Data

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data POL2 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..100] deduced N/A No confident structure predictions are available.
2 View Details [101..136]
[246..534]
PSI-BLAST 274.0 Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase
3 View Details [137..245]
[535..555]
[575..678]
PSI-BLAST 274.0 Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase
4 View Details [556..574]
[679..857]
PSI-BLAST 274.0 Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase
5 View Details [858..1098] PSI-BLAST 13.0 No description for 1b1fR_ was found.
6 View Details [1099..1232] MSA 2.037994 View MSA. No confident structure predictions are available.
7 View Details [1233..1924] deduced N/A No confident structure predictions are available.
8 View Details [1925..2222] MSA 3.018912 View MSA. No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2 No functions predicted.
3 No functions predicted.
4 No functions predicted.
5 No functions predicted.
6
Term Confidence Notes
  • DNA-directed DNA polymerase activity
  • 10.6911520838834 bayes_pls_golite062009
  • DNA polymerase activity
  • 10.645713605123 bayes_pls_golite062009
  • nucleotidyltransferase activity
  • 8.39147983801981 bayes_pls_golite062009
  • DNA primase activity
  • 6.94341770434315 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 4.49699229430126 bayes_pls_golite062009
  • endonuclease activity
  • 4.05835176777658 bayes_pls_golite062009
  • endodeoxyribonuclease activity
  • 4.04079853250282 bayes_pls_golite062009
  • transferase activity
  • 3.80228208941612 bayes_pls_golite062009
  • DNA binding
  • 2.64619844447089 bayes_pls_golite062009
  • nucleic acid binding
  • 2.6018293992859 bayes_pls_golite062009
  • deoxyribonuclease activity
  • 2.53877834217178 bayes_pls_golite062009
  • RNA polymerase activity
  • 2.39159655026329 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
  • 2.39159655026329 bayes_pls_golite062009
  • transcription regulator activity
  • 2.22832306273638 bayes_pls_golite062009
  • ribonuclease activity
  • 2.21640837000075 bayes_pls_golite062009
  • binding
  • 1.84871443682239 bayes_pls_golite062009
  • exonuclease activity
  • 1.38951646742998 bayes_pls_golite062009
  • transcription factor activity
  • 1.18792852183348 bayes_pls_golite062009
  • exoribonuclease activity
  • 0.985835839433199 bayes_pls_golite062009
  • catalytic activity
  • 0.985794797454925 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
  • 0.91438167081716 bayes_pls_golite062009
  • damaged DNA binding
  • 0.903519456111979 bayes_pls_golite062009
  • mismatch repair complex binding
  • 0.893434681603753 bayes_pls_golite062009
  • chromatin binding
  • 0.891218870764102 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
  • 0.589620648556852 bayes_pls_golite062009
  • structure-specific DNA binding
  • 0.431057665208185 bayes_pls_golite062009
  • 3'-5' exonuclease activity
  • 0.427833022898625 bayes_pls_golite062009
  • MutLalpha complex binding
  • 0.419053137349237 bayes_pls_golite062009
  • protein binding
  • 0.366887851366715 bayes_pls_golite062009
  • 0.300511724300705 bayes_pls_golite062009
  • DNA helicase activity
  • 0.280008381637593 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
  • 0.244405458380391 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 0.213302068277253 bayes_pls_golite062009
  • single-stranded DNA binding
  • 0.170862363182338 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 0.152950127352174 bayes_pls_golite062009
  • nuclease activity
  • 0.126991239633667 bayes_pls_golite062009
  • transcription activator activity
  • 0.0924765766526223 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
  • 0.024241485627603 bayes_pls_golite062009
    7 No functions predicted.
    8 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle