YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PRT1

General Information:
Name(s) found: PRT1 / YOR361C [SGD]
Description(s) found:
SHOW ONLY BEST
  • pir||A29562 PRT1 protein - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|6324937|ref|NP_015006.1| Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes; Prt1p [Saccharomyces cerevis [NCBI NR]
  • gi|172286|gb|AAA34917.1| cell cycle regulation and translation initiation protein [NCBI NR]
  • gi|1420784|emb|CAA99690.1| PRT1 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|115936|sp|P06103.1|EIF3B_YEAST RecName: Full=Eukaryotic translation initiation factor 3 subunit B; Short=eIF3b; AltName: Full=Eukaryotic translation initiation factor 3 90 kDa subunit; Short=eIF3 p90; AltName: Full=Translation initiation factor eIF3 p9 [NCBI NR]
  • Eukaryotic translation initiation factor 3 90 kDa subunit - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • Eukaryotic translation initiation factor 3 subunit B OS=Saccharomyces cerevisiae GN=PRT1 PE=1 SV=1 [Swiss-Prot]
  • PRT1 Translation initiation factor eIF3 subunit [mips]
  • eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes [SGD]
  • (P06103) Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 p90) (Cell cycle regulation and translation initiation protein) [4932.FASTACCERV.txt]
  • Chr XV from 1017646-1015355, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 1015354-1017645, reverse complement [yeastorf3.fasta]
  • Chr XV from 1015355-1017646, reverse complement [yeastorf4.fasta]
  • PRT1, Chr XV from 1015354-1017645, reverse complement [yeast_orfs2]
  • PRT1 SGDID:S0005888, Chr XV from 1017648-1015357, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Prt1p [Saccharomyces cerevisiae]gi|1420784|emb|CAA99690.1| PRT1 [Saccharomyces cerevisiae]gi|83436|pir||A29562 PRT1 protein - yeast (Saccharomyces cerevisiae)gi|115936|sp|P06103|IF39_YEAST Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 [nrdb_11152004_Chlamydomonas]
  • PRT1 SGDID:S000005888, Chr XV from 1017648-1015357, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRN [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017650-1015359, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRN [yeast-contam.fasta]
  • PRT1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • cell cycle regulation and translation initiation protein [nr-271106-contam.fasta]
  • Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes; Prt1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 p90) (eIF3b) (Cell cycle regulation and translation initiation protein) [nr-271106-contam.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017650-1015359, reverse complement, Verified ORF, "eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017650-1015359, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017650-1015359, reverse complement, Verified ORF, "eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" [SGDyeast.20101221.fasta]
  • Eukaryotic translation initiation factor 3 subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRT1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017652-1015361, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" [yeast-030211-contam.fasta]
  • PRT1 SGDID:S000005888, Chr XV from 1017652-1015361, Genome Release 64-2-1, reverse complement, Verified ORF, "eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" [20141208_orf_trans.fasta]
  • YOR361C SGDID:S000005888, Chr XV from 1017652-1015361, Genome Release 64-1-1, reverse complement, Verified ORF, "eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: multi-eIF complex [IDALink to PubMed article]
    cytoplasm [IPILink to PubMed article]
    eukaryotic translation initiation factor 3 complex [IDALink to PubMed articleLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    Biological Process: translational initiation [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: translation initiation factor activity [IDALink to PubMed articleLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNFLPRTLK NIYELYFNNI SVHSIVSRNT QLKRSKIIQM TTETFEDIKL EDIPVDDIDF  60
   61 SDLEEQYKVT EEFNFDQYIV VNGAPVIPSA KVPVLKKALT SLFSKAGKVV NMEFPIDEAT 120
  121 GKTKGFLFVE CGSMNDAKKI IKSFHGKRLD LKHRLFLYTM KDVERYNSDD FDTEFREPDM 180
  181 PTFVPSSSLK SWLMDDKVRD QFVLQDDVKT SVFWNSMFNE EDSLVESREN WSTNYVRFSP 240
  241 KGTYLFSYHQ QGVTAWGGPN FDRLRRFYHP DVRNSSVSPN EKYLVTFSTE PIIVEEDNEF 300
  301 SPFTKKNEGH QLCIWDIASG LLMATFPVIK SPYLKWPLVR WSYNDKYCAR MVGDSLIVHD 360
  361 ATKNFMPLEA KALKPSGIRD FSFAPEGVKL QPFRNGDEPS VLLAYWTPET NNSACTATIA 420
  421 EVPRGRVLKT VNLVQVSNVT LHWQNQAEFL CFNVERHTKS GKTQFSNLQI CRLTERDIPV 480
  481 EKVELKDSVF EFGWEPHGNR FVTISVHEVA DMNYAIPANT IRFYAPETKE KTDVIKRWSL 540
  541 VKEIPKTFAN TVSWSPAGRF VVVGALVGPN MRRSDLQFYD MDYPGEKNIN DNNDVSASLK 600
  601 DVAHPTYSAA TNITWDPSGR YVTAWSSSLK HKVEHGYKIF NIAGNLVKED IIAGFKNFAW 660
  661 RPRPASILSN AERKKVRKNL REWSAQFEEQ DAMEADTAMR DLILHQRELL KQWTEYREKI 720
  721 GQEMEKSMNF KIFDVQPEDA SDDFTTIEEI VEEVLEETKE KVE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FUN12 GCD11 HCR1 NIP1 PRT1 RPG1 RPS11A, RPS11B RPS4B, RPS4A RPS8B, RPS8A SUI1 SUI2 SUI3 TIF34 TIF35 TIF5
    View Details (MIPS) Mewes HW, et al. (2004) GCD10 NIP1 PRT1 RPG1 SUI1 TIF34 TIF35
    View Details Krogan NJ, et al. (2006) ADE8 CHZ1 ECM2 HCR1 HEM12 KAP122 NIP1 PRT1 RPG1 SUI1 SYH1 TIF34 TIF35 TIF5 YOR052C
    View Details Gavin AC, et al. (2006) FUN12 HCR1 NIP1 PRT1 RLI1 RPG1 TIF34 TIF35 TIF5
    View Details Gavin AC, et al. (2002) ADE13 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ARX1 ASC1 ATG9 BDF2 BEM2 BMS1 BRX1 BUD20 CAB3 CBF5 CCT5 CCT8 CDC55 CHD1 CIC1 CKA1 CKA2 CKB1 CKB2 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 DYN1 EBP2 ECM5 ERB1 FPR4 FUN12 GCN1 GLT1 GLY1 HAS1 HAT1 HAT2 HCR1 HDA1 HER1 HHF1, HHF2 HIF1 HIS3 HOT1 HSM3 ICL1 IML1 INP2 IPI1 IPI3 IST2 ISW1 ISW2 KAP123 KRE33 KTR5 LHP1 LIP2 LOC1 LSG1 MAC1 MAK21 MAK5 MDN1 MIS1 MRT4 MSB1 NAP1 NIP1 NIP7 NMD3 NMD5 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PFK1 PRO1 PRT1 PSD2 PSE1 PSH1 PUF6 REI1 RET1 RIC1 RIX1 RIX7 RLI1 RLP24 RLP7 RPA135 RPA190 RPC40 RPF1 RPF2 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPP2B RPT2 RPT3 RPT5 RPT6 RRP1 RRP12 RSA3 RSA4 RSC3 RTR1 RVB2 SAM1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SPT16 SPT5 SSA4 SSF1 SUA7 SUI1 SUI2 SUI3 SUP45 TEL1 TIF34 TIF35 TIF5 TIF6 TSC11 TUB3 URB1 USO1 UTP10 UTP20 UTP22 UTP6 VPS1 VTH2 YFR006W YGL036W YGR102C YPR077C YTA7 YTM1
    View Details Qiu et al. (2008) CLU1 FUN12 GCD11 HCR1 NIP1 PRT1 RPG1 SUI1 SUI2 SUI3 TIF34 TIF35 TIF5 YGR054W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PRT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] PSI-BLAST 16.69897 Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
    2 View Details [161..679] PSI-BLAST 37.522879 Actin interacting protein 1
    3 View Details [680..763] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  4.50438526063124 bayes_pls_golite062009
  • translation initiation factor activity
    		•  3.27900316559423 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.03004688154589 bayes_pls_golite062009
  • mRNA binding
    		•  2.92795844574986 bayes_pls_golite062009
  • binding
    		•  2.80563734517858 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
    		• 1.49431666307335 bayes_pls_golite062009
  • protein binding
    		•  1.02232785292059 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.90573796517364 bayes_pls_golite062009
  • RNA cap binding
    		•  0.847034036194541 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.32812362201346 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
    2
    Term Confidence Notes
  • structural molecule activity
    		•  2.6914565031145 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.29806492548141 bayes_pls_golite062009
  • binding
    		•  1.58733371663063 bayes_pls_golite062009
  • RNA binding
    		•  1.54614730254863 bayes_pls_golite062009
    		• 1.53488375271101 bayes_pls_golite062009
  • protein binding
    		•  1.11897341394404 bayes_pls_golite062009
  • snoRNA binding
    		•  0.503568445551651 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.417970425588631 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle