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Protein Overview: ARC19

General Information:
Name(s) found: ARC19 / YKL013C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 171 amino acids

    Gene Ontology:
    Cellular Component: Arp2/3 protein complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: mitochondrion inheritance [TASLink to PubMed article]
    actin cortical patch assembly [IMPLink to PubMed article]
    Molecular Function: structural molecule activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQSLRPYLT AVRYSLEAAL TLSNFSSQEV ERHNRPEVEV PNTSAELLLQ PMHISRNENE  60
   61 QVLIEPSVNS VRMSLMVKQA DEIEQILVHK FTRFLEQRAE AFYILRRVPI PGYSISFLIT 120
  121 NKHTESMKTG KLVDFIIEFM EDVDKEISEI KLFLNARARF VAEAYLDEFV Y

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3
    View Details (MIPS) Mewes HW, et al. (2004) ARC15 ARC18 ARC19 ARC35 ARP2 ARP3
    View Details Krogan NJ, et al. (2006) ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 PAC1 TAP42
    View Details Gavin AC, et al. (2006) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3
    View Details Gavin AC, et al. (2002) ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 CCT5 CCT8 NOG2 PFK1 PRT1
    View Details Ho Y, et al. (2002) ADR1 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ATP3 BNI1 DUR1,2 FET3 GFA1 IMH1 KAP122 MCM4 MCM7 MET18 PST2 PUF3 RPN8 RPT4 RVB1 TRP3 YJR029W
    View Details Qiu et al. (2008) ARC15 ARC18 ARC19 ARC35 ARP2 ARP3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen AIM7 ARC19 2 Uetz P, et al. (2000)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ARC19 and SAC6 Huh WK, et al. (2003)
    View Data ARC19 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 596.221849 ARPC4 (20 kDa subunit)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  6.0922573068519 bayes_pls_golite062009
  • actin filament binding
    		•  5.01990273175321 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.64781612293343 bayes_pls_golite062009
  • binding
    		•  2.16088008530271 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.37010524302636 bayes_pls_golite062009
  • protein binding
    		•  0.932082028882932 bayes_pls_golite062009
  • structural molecule activity
    		•  0.83499804393822 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle