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View Structure Prediction Details

Protein: ARC19
Organism: Saccharomyces cerevisiae
Length: 171 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARC19.

Description E-value Query
Range
Subject
Range
ARPC4 - actin related protein 2/3 complex, subunit 4, 20kDa
gi|195562233 - gi|195562233|gb|ACG50184.1| actin related protein 2/3 complex subunit 4 [Sus scrofa]
gi|57100910 - gi|57100910|ref|XP_533747.1| PREDICTED: similar to actin related protein 2/3 complex, subunit 4 [Can...
gi|157169642 - gi|157169642|gb|AAI52791.1| Actin related protein 2/3 complex, subunit 4, 20kDa [synthetic construct...
ENSCJAT00000031460 - null
ARPC4_MOUSE - Actin-related protein 2/3 complex subunit 4 OS=Mus musculus GN=Arpc4 PE=1 SV=3
tr|G3GX96|G3GX96... - Actin-related protein 2/3 complex subunit 4 OS=Cricetulus griseus GN=I79_002331 PE=3 SV=1
tr|F6PH57|F6PH57... - Actin-related protein 2/3 complex subunit 4 OS=Equus caballus OX=9796 GN=ARPC4 PE=3 SV=1
ARPC4_BOVIN - Actin-related protein 2/3 complex subunit 4 OS=Bos taurus GN=ARPC4 PE=1 SV=3
gi|187469309, gi... - gi|34858314|ref|XP_238365.2| PREDICTED: similar to actin related protein 2/3 complex, subunit 4 [Rat...
gi|160904173 - gi|160904173|gb|ABX52159.1| actin related protein 2/3 complex, subunit 4, 20kDa, isoform 3 (predicte...
2.0E-75 [1..169] [1..168]
gi|12857620 - gi|12857620|dbj|BAB31059.1| unnamed protein product [Mus musculus]
3.0E-75 [1..169] [1..168]
CRE20305 - RP20505 WBGene00061677 locus:Cre-arx-6 status:Confirmed
arx-6 - status:Partially_confirmed UniProt:P58798 protein_id:AAK93841.1
1.0E-74 [1..169] [1..168]
gi|2760013 - gi|2760013|emb|CAA11175.1| actin related protein [Lumbricus rubellus]
3.0E-73 [1..169] [1..168]
ORFP:13528 - YKL013C, Contig c407 40648-41163
gi|190409809 - gi|190409809|gb|EDV13074.1| ARP2/3 complex 20 kDa subunit [Saccharomyces cerevisiae RM11-1a]
ARC19 - Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin pa...
ARPC4_YEAST - Actin-related protein 2/3 complex subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
gi|151941532 - gi|151941532|gb|EDN59895.1| arp2/3 complex subunit [Saccharomyces cerevisiae YJM789]
2.0E-70 [1..171] [1..171]
ARPC4_DICDI - Actin-related protein 2/3 complex subunit 4 OS=Dictyostelium discoideum GN=arcD PE=1 SV=1
gi|60473963, gi|... - gi|66826119|ref|XP_646414.1| actin related protein 2/3 complex, 20 kDa subunit [Dictyostelium discoi...
3.0E-70 [1..169] [1..168]
arc4 - ARP2 /3 actin-organizing complex subunit Arc4
ARPC4_SCHPO - Actin-related protein 2/3 complex subunit 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
6.0E-70 [1..169] [1..168]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQSLRPYLT AVRYSLEAAL TLSNFSSQEV ERHNRPEVEV PNTSAELLLQ PMHISRNENE  60
   61 QVLIEPSVNS VRMSLMVKQA DEIEQILVHK FTRFLEQRAE AFYILRRVPI PGYSISFLIT 120
  121 NKHTESMKTG KLVDFIIEFM EDVDKEISEI KLFLNARARF VAEAYLDEFV Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 596.221849
Match: 1k8kF_
Description: ARPC4 (20 kDa subunit)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 6.0922573068519 bayes_pls_golite062009
actin filament binding 5.01990273175321 bayes_pls_golite062009
cytoskeletal protein binding 4.64781612293343 bayes_pls_golite062009
binding 2.16088008530271 bayes_pls_golite062009
structural constituent of cytoskeleton 1.37010524302636 bayes_pls_golite062009
protein binding 0.932082028882932 bayes_pls_golite062009
structural molecule activity 0.83499804393822 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle