YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: ECM5

General Information:
Name(s) found: ECM5 / YMR176W [SGD]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1411 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGHDSVTKI SHILNEPVNE KVMVQNGFHE SSKIADIELE IQERPSIKQW ESPRSAVIPT  60
   61 SNHNFSPFLY TQFKSRGAAP FAPETIKSVD LVELPEGVPA RVFHEKTGLF YQISPHSIPT 120
  121 FILAKKELPD PIKFYELVED LGSVYGCVKL KIIPDADKFT QLNVDVDRLW FKARKQFFNS 180
  181 NEFQRTKIVD FYAKLYNFHN KIKKSTLTRI PSIDKRTLDL YRLRSCVKLR GGFNAVCEKK 240
  241 LWAQIGRELG YSGRIMSSLS TSLRSAYAKI LLDFDIYEEE EQAARNNEKN EDMVESEIFR 300
  301 HSNSRSRDEE EPLHKKAKIH RDVFRAGSIN HEFKRMRDIK HIKGFPTYFN SLTEFKLGYT 360
  361 QSTETTLPGY DFTFWENGME IYDKSKYETK TSPVYNLRQY YEKSLAVFTA IVAKFGSSYP 420
  421 DLFAKHTTLP QKEFERLYFH LLSEHFIDFE IDTGLGLPCS MRSPGNNSSN EKFAIKNILD 480
  481 QWNLDNIPLN ELSLLQHLDL DMANFTRTTY DIGMLFSCQG WSVSDHFLPS IDFNHLGSTK 540
  541 LVYSIAPKDM EKFEALIARG KSEWDTIQSR PRYSTSDDEL KSFIETDFYK SFLDAEQSAD 600
  601 YSNTGDNSKN SFPEDKIAGN TLHDGSQSDF IFEPNFILAN GIKLYKTTQE QGSYIFKFPK 660
  661 AFTCSIGSGF YLSQNAKFAP SSWLRFSSEA AKWTSKMGFL PGLDVNQLLI NALLNSNNPV 720
  721 LRKKCRDLIS NYVVEEAENS KKLGELIGTV DVVYNKLNYI SDISLESTGL SKIVVTHGAL 780
  781 QRNLSLKEFV VLLEKPENGA HSICGIPIRD QSGNLNVCLH SYFDSASLGI ALDGLDKPPT 840
  841 SYLLVHNEDF EKKWDVLMTS TFRNRTVPLN IIQYLISHTD SNTEFNRMLR SNFDDSLLLI 900
  901 EKCKKFIKTF VDVSCSVKDV DFGNGFNLRH LPLKFSDNMA DNLESLYESV RKCSIEFSEK 960
  961 PTIIRLYHVS RQFPIDNRDI IDGNNLDLLK ELYQKSLTIP LKVSYWTKLT RKICRLEWLS1020
 1021 VYEHIFIERC DIKNEDPAKY SLPLLYSYFE FGLKYCDSED IDKLGEVRKL ILKYQDMMQK1080
 1081 VRVFLKKDPP SKISLSDLED VLLDIEEYRL PIQSSFFSEL DYVIREIENA KKMNDVNILY1140
 1141 NTDNIDKIDE LIRKNDPKFV KFANQFNGSR LDKRPLASDN SGSVKAKQEL KVFKLWNQHL1200
 1201 DQIMQKNKFI EILPSIFRCL DLKSDKYIPL ESCSKRQTKY CFCRRVEEGT AMVECEICKE1260
 1261 WYHVDCISNG ELVPPDDPNV LFVCSICTPP CMAVDNIEGV TFELDDLKRI LVESLKLSLI1320
 1321 PDPPILKNLF DVFAFALNFK NEMEKELFTN GYVNQLSSTH KIKYYLRKLK GSQCGFTNLT1380
 1381 DPLRKHCQVK DAEAIKWLTD NGRIIITGIP N

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ECM5 IML1 NMD5 PSD2 PSH1 YFR006W
    View Details Gavin AC, et al. (2002) BDF2 CDC55 CKB1 DYN1 ECM5 GLY1 HAT1 HAT2 HHF1, HHF2 HIF1 HSM3 ICL1 IML1 KAP123 KRE33 LIP2 MAC1 MDN1 MIS1 MSB1 NIP1 NMD5 PFK1 PRO1 PRT1 PSD2 PSE1 PSH1 RPA135 RPC40 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPT2 RPT3 RPT5 RPT6 RSC3 SAM1 TEL1 TSC11 USO1 UTP20 VTH2 YFR006W YPR077C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #27 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps3-5 Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ECM5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..211] PSI-BLAST 91.0103 DNA-binding domain from the dead ringer protein
    3 View Details [212..317] PSI-BLAST 91.0103 DNA-binding domain from the dead ringer protein
    4 View Details [318..394] deduced N/A No confident structure predictions are available.
    5 View Details [395..739] MSA 9.11995 View MSA. No confident structure predictions are available.
    6 View Details [740..824] deduced N/A No confident structure predictions are available.
    7 View Details [825..886] PSI-BLAST 4.09691 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
    8 View Details [887..1219] PSI-BLAST 23.30103 Heavy meromyosin subfragment
    9 View Details [1220..1299] PSI-BLAST 2.30103 Nuclear corepressor KAP-1 (TIF-1beta)
    10 View Details [1300..1411] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.82429745664596 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.96196521368194 bayes_pls_golite062009
  • DNA binding
    		•  1.95175882800914 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.69129851237145 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.9777334079728 bayes_pls_golite062009
  • protein binding
    		•  0.923807406971133 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.89101605547219 bayes_pls_golite062009
  • transcription activator activity
    		•  0.302416902310042 bayes_pls_golite062009
  • transcription factor activity
    		•  0.143417837230029 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0217863068537998 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle